ZFIN ID: ZDB-PUB-990427-10
A new ß-globin gene from the zebrafish, betaE1, and its pattern of transcription during embryogenesis
Quinkertz, A. and Campos-Ortega, J.A.
Date: 1999
Source: Development genes and evolution   209(2): 126-131 (Journal)
Registered Authors: Campos-Ortega, Jose, Quinkertz, Andre
Keywords: globin genes; transcription pattern; erythropoiesis; zebrafish
MeSH Terms:
  • Animals
  • Cell Lineage
  • DNA, Complementary/genetics
  • Gene Expression Regulation, Developmental*
  • Globins/genetics*
  • Transcription, Genetic
  • Zebrafish/embryology*
  • Zebrafish/genetics*
PubMed: 10022956 Full text @ Dev. Genes Evol.
In a search for novel, developmentally regulated genes we screened randomly picked cDNA clones, obtained from zebrafish mRNA, by in situ hybridization with digoxigenin-labelled riboprobes. Out of 150 clones tested, 1 codes for a new beta-globin gene and is expressed during embryogenesis. Here we describe its pattern of expression and its use as marker for early zebrafish erythropoiesis.