PUBLICATION
Zebrafish genomics: from mutants to genes
- Authors
- Postlethwait, J.H. and Talbot, W.S.
- ID
- ZDB-PUB-970602-15
- Date
- 1997
- Source
- Trends in genetics : TIG 13(5): 183-190 (Review)
- Registered Authors
- Postlethwait, John H., Talbot, William S.
- Keywords
- none
- MeSH Terms
-
- Animals
- Chromosome Mapping*
- Cloning, Molecular/methods
- Mutation*
- Zebrafish/genetics*
- PubMed
- 9154001 Full text @ Trends Genet.
Citation
Postlethwait, J.H. and Talbot, W.S. (1997) Zebrafish genomics: from mutants to genes. Trends in genetics : TIG. 13(5):183-190.
Abstract
Exquisite embryonic lethal mutations have been isolated in hundreds of genes necessary for zebrafish development. Analysis of this resource promises to enhance our understanding of the molecular genetic mechanisms of vertebrate development. This review discusses the state of the zebrafish genome project and the genetic trickery that can expedite molecular isolation of genes disrupted by these mutations.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping