ZFIN ID: ZDB-PUB-970602-15
Zebrafish genomics: from mutants to genes
Postlethwait, J.H. and Talbot, W.S.
Date: 1997
Source: Trends in genetics : TIG 13(5): 183-190 (Review)
Registered Authors: Postlethwait, John H., Talbot, William S.
Keywords: none
MeSH Terms: Animals; Chromosome Mapping*; Cloning, Molecular/methods; Mutation*; Zebrafish/genetics*
PubMed: 9154001 Full text @ Trends Genet.
ABSTRACT
Exquisite embryonic lethal mutations have been isolated in hundreds of genes necessary for zebrafish development. Analysis of this resource promises to enhance our understanding of the molecular genetic mechanisms of vertebrate development. This review discusses the state of the zebrafish genome project and the genetic trickery that can expedite molecular isolation of genes disrupted by these mutations.
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