ZFIN ID: ZDB-PUB-961014-919
Segregation and early dispersal of neural crest cells in the embryonic zebrafish
Raible, D.W., Wood, A., Hodsdon, W., Henion, P.D., Weston, J.A., and Eisen, J.S.
Date: 1992
Source: Developmental dynamics : an official publication of the American Association of Anatomists 195: 29-42 (Journal)
Registered Authors: Eisen, Judith S., Henion, Paul, Raible, David, Weston, James A.
Keywords: Cell migration, Basal lamina, Teleost, Brachydanio rerio
MeSH Terms: Animals; Cell Movement; Neural Crest*; Peripheral Nerves/embryology*; Zebrafish/embryology*
PubMed: 1292751 Full text @ Dev. Dyn.
ABSTRACT
We have exploited our ability to visualize and follow individual cells in situ, in the living embryo, to study the development of trunk neural crest in the embryonic zebrafish. In most respects, the development of zebrafish trunk neural crest is similar to the development of trunk neural crest in other species: zebrafish trunk neural crest cells segregate from the dorsal neural keel in a rostrocaudal sequence, migrate ventrally along two pathways, and give rise to neurons of the peripheral nervous system, Schwann cells, and pigment cells. However, some aspects of the development of zebrafish trunk neural crest differ from those of other vertebrates: zebrafish trunk neural crest cells are significantly larger and fewer in number than those in avian embryos and the locations of their migratory pathways are slightly different. This initial description of neural crest development in the zebrafish embryo provides the foundation for future experimental studies.
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