ZFIN ID: ZDB-PUB-961014-893
Noninvasive recording of the Mauthner neuron action potential in larval zebrafish (Brachydanio rerio)
Prugh, J.I.P., Kimmel, C.B., and Metcalfe, W.K.
Date: 1982
Source: The Journal of experimental biology   101: 83-92 (Journal)
Registered Authors: Kimmel, Charles B., Metcalfe, Walt
Keywords: none
MeSH Terms:
  • Action Potentials
  • Animals
  • Brain/physiology
  • Goldfish
  • Larva
  • Microelectrodes
  • Neurons/physiology*
PubMed: 7166698
We describe the identification of Mauthner (M-) cell action potentials in an intact zebrafish larva, utilizing recording electrodes located outside the fish: 1. The externally recorded spike occurs at approximately the same time, and its waveform changes with recording site in the same way, as the extracellular M-spike recorded within the central nervous system. 2. The externally recorded M-spike may be readily distinguished from other forms of neural activity. 3. The M-spike can be identified in recordings from unrestrained larvae. This finding permits the direct study of M-cell function in the freely behaving animal.