PUBLICATION
Noninvasive recording of the Mauthner neuron action potential in larval zebrafish (Brachydanio rerio)
- Authors
- Prugh, J.I.P., Kimmel, C.B., and Metcalfe, W.K.
- ID
- ZDB-PUB-961014-893
- Date
- 1982
- Source
- The Journal of experimental biology 101: 83-92 (Journal)
- Registered Authors
- Kimmel, Charles B., Metcalfe, Walt
- Keywords
- none
- MeSH Terms
-
- Action Potentials
- Animals
- Brain/physiology
- Goldfish
- Larva
- Microelectrodes
- Neurons/physiology*
- PubMed
- 7166698 Full text @ J. Exp. Biol.
Citation
Prugh, J.I.P., Kimmel, C.B., and Metcalfe, W.K. (1982) Noninvasive recording of the Mauthner neuron action potential in larval zebrafish (Brachydanio rerio). The Journal of experimental biology. 101:83-92.
Abstract
We describe the identification of Mauthner (M-) cell action potentials in an intact zebrafish larva, utilizing recording electrodes located outside the fish: 1. The externally recorded spike occurs at approximately the same time, and its waveform changes with recording site in the same way, as the extracellular M-spike recorded within the central nervous system. 2. The externally recorded M-spike may be readily distinguished from other forms of neural activity. 3. The M-spike can be identified in recordings from unrestrained larvae. This finding permits the direct study of M-cell function in the freely behaving animal.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping