ZFIN ID: ZDB-PUB-961014-893
Noninvasive recording of the Mauthner neuron action potential in larval zebrafish (Brachydanio rerio)
Prugh, J.I.P., Kimmel, C.B., and Metcalfe, W.K.
We describe the identification of Mauthner (M-) cell action potentials in an intact zebrafish larva, utilizing recording electrodes located outside the fish: 1. The externally recorded spike occurs at approximately the same time, and its waveform changes with recording site in the same way, as the extracellular M-spike recorded within the central nervous system. 2. The externally recorded M-spike may be readily distinguished from other forms of neural activity. 3. The M-spike can be identified in recordings from unrestrained larvae. This finding permits the direct study of M-cell function in the freely behaving animal.
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