PUBLICATION
Brain neurons which project to the spinal cord in young larvae of the zebrafish
- Authors
- Kimmel, C.B., Powell, S.L., and Metcalfe, W.K.
- ID
- ZDB-PUB-961014-594
- Date
- 1982
- Source
- The Journal of comparative neurology 205: 112-127 (Journal)
- Registered Authors
- Kimmel, Charles B., Metcalfe, Walt
- Keywords
- none
- MeSH Terms
-
- Brain/anatomy & histology*
- Brain Mapping
- Animals
- Spinal Cord/anatomy & histology*
- Vestibular Nuclei/anatomy & histology
- Vestibular Nuclei/cytology
- Efferent Pathways/anatomy & histology
- Fishes/anatomy & histology*
- Lampreys/anatomy & histology
- Reticular Formation/anatomy & histology
- Reticular Formation/cytology
- PubMed
- 7076887 Full text @ J. Comp. Neurol.
Citation
Kimmel, C.B., Powell, S.L., and Metcalfe, W.K. (1982) Brain neurons which project to the spinal cord in young larvae of the zebrafish. The Journal of comparative neurology. 205:112-127.
Abstract
A small number of brain neurons project to caudal levels of the spinal cord in the larva of the teleost Brachydanio rerio. These cells were identified in animals 6 days after fertilization by backfilling with horseradish peroxidase following transection of the cord at the level of the cloaca. In preparations with the most labeled cells a total of 30-40 were present on each side of the midline. They were located within three regions of the brainstem: the midbrain nucleus of origin of the medial longitudinal fascicle (mlf), the hindbrain reticular formation, and the hindbrain vestibular nucleus. A total of 15 classes of cells could be distinguished by soma positions, dendritic fields, and axonal pathways. For some of these classes only one or two cells were usually present on each side of the brain. Most of the labeled cells contributed axons to the mlf ipsilateral to the soma; however, the Mauthner cells and three new types of hindbrain reticulospinal reticulospinal cells have decussating axons that enter the contralateral mlf. The observed distribution of labeled reticulospinal cells is similar to that previously described for large reticular cells in adult teleosts and to the system of identified Mauthner and Muller cells in the lamprey.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping