PUBLICATION
Automatic Gene Ontology annotation based on Rhea mapping
- Authors
- ZFIN Staff
- ID
- ZDB-PUB-221108-20
- Date
- 2022
- Source
- Automated Data Submission : (Curation)
- Registered Authors
- Keywords
- none
- MeSH Terms
- none
- PubMed
- none
Citation
ZFIN Staff (2022) Automatic Gene Ontology annotation based on Rhea mapping. Automated Data Submission. .
Abstract
Rhea (https://www.rhea-db.org/, PMID:30272209) is an expert-curated knowledgebase of chemical and transport reactions of biological interest - and the standard for enzyme and transporter annotation in UniProtKB (PMID:31688925). Rhea uses the chemical dictionary ChEBI (Chemical Entities of Biological Interest) to describe reaction participants and their chemical transformations in a computationally tractable manner. GO terms corresponding to Rhea reactions are assigned a Rhea database cross-reference. The corresponding GO term is automatically applied to all UniProt entries annotated with a Rhea reaction. The mapping file is available at: http://current.geneontology.org/ontology/external2go/rhea2go. ZFIN gets these annotations in a data load from GOA (www.ebi.ac.ukGOA).
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping