PUBLICATION
The eye tugs and the nose follows: how inter-tissue adhesion directs olfactory development
- Authors
- Smith, S.J., Holley, S.A.
- ID
- ZDB-PUB-211216-15
- Date
- 2021
- Source
- EMBO reports 23(2): e54396 (Other)
- Registered Authors
- Holley, Scott
- Keywords
- none
- MeSH Terms
-
- Tissue Adhesions
- Animals
- Organogenesis/genetics
- Zebrafish Proteins*/metabolism
- Ectoderm/metabolism
- Zebrafish*/embryology
- PubMed
- 34910840 Full text @ EMBO Rep.
Citation
Smith, S.J., Holley, S.A. (2021) The eye tugs and the nose follows: how inter-tissue adhesion directs olfactory development. EMBO reports. 23(2):e54396.
Abstract
Embryonic development is a complex process in which cells divide, migrate, and differentiate in a precise spatiotemporal pattern. Cell-cell communication among neighboring cells plays a central role in specifying cell fate and in coordinating development. Embryonic development also relies on physical interaction between cells and coordinated changes in cell shape. A more recently investigated phenomenon is the coupling of development of adjacent tissues via inter-tissue adhesion. In this issue of EMBO Reports, Monnot and colleagues identify a role for inter-tissue adhesion in the development of adjacent sensory organs in the zebrafish. Specifically, eye morphogenesis influences the organ shape and retrograde axon growth in the adjacent olfactory placode via a shared extracellular matrix.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping