PUBLICATION
Acid-Sensing Ion Channels in Zebrafish
- Authors
- Montalbano, G., Levanti, M., Mhalhel, K., Abbate, F., Laurà, R., Guerrera, M.C., Aragona, M., Germanà, A.
- ID
- ZDB-PUB-210828-4
- Date
- 2021
- Source
- Animals : an open access journal from MDPI 11(8): (Review)
- Registered Authors
- Aragona, Maria Luisa, Germanà, Antonino, Guerrera, Maria Cristina, Mhalhel, Kamel, Montalbano, Giuseppe
- Keywords
- ASICs, brain, gills, gut, ion channels, sensory organs, zebrafish
- MeSH Terms
- none
- PubMed
- 34438928 Full text @ Animals (Basel)
Citation
Montalbano, G., Levanti, M., Mhalhel, K., Abbate, F., Laurà, R., Guerrera, M.C., Aragona, M., Germanà, A. (2021) Acid-Sensing Ion Channels in Zebrafish. Animals : an open access journal from MDPI. 11(8):.
Abstract
The ASICs, in mammals as in fish, control deviations from the physiological values of extracellular pH, and are involved in mechanoreception, nociception, or taste receptions. They are widely expressed in the central and peripheral nervous system. In this review, we summarized the data about the presence and localization of ASICs in different organs of zebrafish that represent one of the most used experimental models for the study of several diseases. In particular, we analyzed the data obtained by immunohistochemical and molecular biology techniques concerning the presence and expression of ASICs in the sensory organs, such as the olfactory rosette, lateral line, inner ear, taste buds, and in the gut and brain of zebrafish.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping