PUBLICATION
Transcriptome Analysis of Zebrafish Olfactory Epithelium Reveal Sexual Differences in Odorant Detection
- Authors
- Wang, Y., Jiang, H., Yang, L.
- ID
- ZDB-PUB-200601-1
- Date
- 2020
- Source
- Genes 11(6): (Journal)
- Registered Authors
- Keywords
- alternative splicing, chemosensory receptor, olfactory epithelium, sexual dimorphism, zebrafish
- MeSH Terms
-
- Animals
- Female
- High-Throughput Nucleotide Sequencing
- Male
- Odorants/analysis*
- Olfactory Mucosa/metabolism*
- RNA-Seq
- Sex Characteristics
- Transcriptome/genetics*
- Zebrafish/genetics*
- Zebrafish/physiology
- PubMed
- 32471067 Full text @ Genes (Basel)
Citation
Wang, Y., Jiang, H., Yang, L. (2020) Transcriptome Analysis of Zebrafish Olfactory Epithelium Reveal Sexual Differences in Odorant Detection. Genes. 11(6):.
Abstract
Animals have evolved a large number of olfactory receptor genes in their genome to detect numerous odorants in their surrounding environments. However, we still know little about whether males and females possess the same abilities to sense odorants, especially in fish. In this study, we used deep RNA sequencing to examine the difference of transcriptome between male and female zebrafish olfactory epithelia. We found that the olfactory transcriptomes between males and females are highly similar. We also found evidence of some genes showing differential expression or alternative splicing, which may be associated with odorant-sensing between sexes. Most chemosensory receptor genes showed evidence of expression in the zebrafish olfactory epithelium, with a higher expression level in males than in females. Taken together, our results provide a comprehensive catalog of the genes mediating olfactory perception and pheromone-evoked behavior in fishes.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping