PUBLICATION
Effects of pH and nitrites on the toxicity of a cypermethrin-based pesticide to zebrafish embryos
- Authors
- Soares, M.P., Machado, A.L., Hayd, L., Soares, A., Domingues, I.
- ID
- ZDB-PUB-200221-10
- Date
- 2020
- Source
- Environmental Toxicology and Pharmacology 76: 103351 (Journal)
- Registered Authors
- Soares, Amadeu
- Keywords
- Barrage®, Changed toxicity, Danio rerio, Environmental risk, Physicochemical water properties
- MeSH Terms
-
- Animals
- Embryo, Nonmammalian/drug effects*
- Hydrogen-Ion Concentration
- Insecticides/toxicity*
- Nitrites/toxicity*
- Pyrethrins/toxicity*
- Toxicity Tests
- Water Pollution, Chemical
- Zebrafish
- PubMed
- 32062415 Full text @ Environ. Toxicol. Pharmacol.
Citation
Soares, M.P., Machado, A.L., Hayd, L., Soares, A., Domingues, I. (2020) Effects of pH and nitrites on the toxicity of a cypermethrin-based pesticide to zebrafish embryos. Environmental Toxicology and Pharmacology. 76:103351.
Abstract
Physical and chemical water parameters have an important role on the toxicity of environmental contaminants by affecting their degradation, transformation and bioavailability. The objective of this study was to evaluate the effects of pH and nitrite variation on the toxicity of the cypermethrin based pesticide Barrage®. Zebrafish embryos (Danio rerio) were exposed to a combination of pH or nitrite and cypermethrin through the Barrage® formulation for 96 h and lethal and developmental endpoints assessed. Concerning mortality, pH seemed to increase Barrage® toxicity, while nitrite concentrations tested did not seem to change Barrage® lethality. At sublethal level, either for combinations involving pH or nitrites, results suggested some interactive effects of environmental and chemical factors, highlighting the need of further research. This work suggests that sublethal endpoints should be included in the assessment of combined effects of compounds given that they can provide important information not obtained through lethality.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping