PUBLICATION
UPLC/MS MS data of testosterone metabolites in human and zebrafish liver microsomes and whole zebrafish larval microsomes
- Authors
- Saad, M., Bijttebier, S., Matheeussen, A., Verbueken, E., Pype, C., Casteleyn, C., Van Ginneken, C., Maes, L., Cos, P., Van Cruchten, S.
- ID
- ZDB-PUB-180316-6
- Date
- 2017
- Source
- Data in brief 16: 644-648 (Other)
- Registered Authors
- Van Cruchten, Steven, Verbueken, Evy
- Keywords
- none
- MeSH Terms
- none
- PubMed
- 29541660 Full text @ Data Brief
Citation
Saad, M., Bijttebier, S., Matheeussen, A., Verbueken, E., Pype, C., Casteleyn, C., Van Ginneken, C., Maes, L., Cos, P., Van Cruchten, S. (2017) UPLC/MS MS data of testosterone metabolites in human and zebrafish liver microsomes and whole zebrafish larval microsomes. Data in brief. 16:644-648.
Abstract
This article represents data regarding a study published in Toxicology in vitro entitled " in vitro CYP-mediated drug metabolism in the zebrafish (embryo) using human reference compounds" (Saad et al., 2017) [1]. Data were acquired with ultra-performance liquid chromatography - accurate mass mass spectrometry (UPLC-amMS). A full spectrum scan was conducted for the testosterone (TST) metabolites from the microsomal stability assay in zebrafish and humans. The microsomal proteins were extracted from adult zebrafish male (MLM) and female (FLM) livers, whole body homogenates of 96 h post fertilization larvae (EM) and a pool of human liver microsomes from 50 donors (HLM). Data are expressed as the abundance from the extracted ion chromatogram of the metabolites.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping