PUBLICATION

Landmark detection in 2D bioimages for geometric morphometrics: a multi-resolution tree-based approach

Authors
Vandaele, R., Aceto, J., Muller, M., Péronnet, F., Debat, V., Wang, C.W., Huang, C.T., Jodogne, S., Martinive, P., Geurts, P., Marée, R.
ID
ZDB-PUB-180113-9
Date
2018
Source
Scientific Reports   8: 538 (Journal)
Registered Authors
Muller, Marc
Keywords
none
MeSH Terms
  • Algorithms
  • Animals
  • Body Weights and Measures/methods*
  • Body Weights and Measures/standards
  • Drosophila
  • Humans
  • Image Processing, Computer-Assisted/methods*
  • Software
  • Zebrafish
PubMed
29323201 Full text @ Sci. Rep.
Abstract
The detection of anatomical landmarks in bioimages is a necessary but tedious step for geometric morphometrics studies in many research domains. We propose variants of a multi-resolution tree-based approach to speed-up the detection of landmarks in bioimages. We extensively evaluate our method variants on three different datasets (cephalometric, zebrafish, and drosophila images). We identify the key method parameters (notably the multi-resolution) and report results with respect to human ground truths and existing methods. Our method achieves recognition performances competitive with current existing approaches while being generic and fast. The algorithms are integrated in the open-source Cytomine software and we provide parameter configuration guidelines so that they can be easily exploited by end-users. Finally, datasets are readily available through a Cytomine server to foster future research.
Genes / Markers
Figures
Show all Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping