PUBLICATION
Zebrafish Behavior: Opportunities and Challenges
- Authors
- Orger, M.B., de Polavieja, G.G.
- ID
- ZDB-PUB-170405-1
- Date
- 2017
- Source
- Annual review of neuroscience 40: 125-147 (Review)
- Registered Authors
- Orger, Mike
- Keywords
- none
- MeSH Terms
-
- Animals
- Behavior, Animal/physiology*
- Brain/physiology*
- Neurons/physiology*
- Social Behavior*
- Zebrafish
- PubMed
- 28375767 Full text @ Ann. Rev. Neurosci.
Citation
Orger, M.B., de Polavieja, G.G. (2017) Zebrafish Behavior: Opportunities and Challenges. Annual review of neuroscience. 40:125-147.
Abstract
A great challenge in neuroscience is understanding how activity in the brain gives rise to behavior. The zebrafish is an ideal vertebrate model to address this challenge, thanks to the capacity, at the larval stage, for precise behavioral measurements, genetic manipulations, and recording and manipulation of neural activity noninvasively and at single-neuron resolution throughout the whole brain. These techniques are being further developed for application in freely moving animals and juvenile stages to study more complex behaviors including learning, decision making, and social interactions. We review some of the approaches that have been used to study the behavior of zebrafish and point to opportunities and challenges that lie ahead. Expected final online publication date for the Annual Review of Neuroscience Volume 40 is July 8, 2017. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping