PUBLICATION
Zebrafish olfactory receptor ORA1 recognizes a putative reproductive pheromone
- Authors
- Ahuja, G., Korsching, S.
- ID
- ZDB-PUB-170214-287
- Date
- 2014
- Source
- Communicative & integrative biology 7(5): (Review)
- Registered Authors
- Ahuja, Gaurav, Korsching, Sigrun
- Keywords
- V1R-like, calcium imaging, heterologous expression, oviposition, pheromone, tyrosine, zebrafish
- MeSH Terms
- none
- PubMed
- 26842458 Full text @ Commun. Integr. Biol.
Citation
Ahuja, G., Korsching, S. (2014) Zebrafish olfactory receptor ORA1 recognizes a putative reproductive pheromone. Communicative & integrative biology. 7(5).
Abstract
Teleost v1r-related ora genes constitute a small and highly conserved olfactory receptor gene family, and their direct orthologs are present in lineages as distant as cartilaginous fishes. Recently, the first member of the ora gene family was deorphanized. ORA1 detects p-hydroxyphenylacetic acid with high sensitivity and specificity. This compound elicits olfactory-mediated oviposition behavior in adult zebrafish mating pairs, suggesting a potential function as a reproductive pheromone for pHPAA itself or a related substance. This association of an odor and its cognate receptor with an oviposition response may provide a molecular basis for studying neural circuits involved in fish reproduction.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping