PUBLICATION
Transvection Arising from Transgene Interactions in Zebrafish
- Authors
- Keefe, M.D., Bonkowsky, J.L.
- ID
- ZDB-PUB-161026-4
- Date
- 2017
- Source
- Zebrafish 14(1): 8-9 (Journal)
- Registered Authors
- Bonkowsky, Joshua, Keefe, Matthew
- Keywords
- Gal4, UAS, transgenic, transvection, zebrafish
- MeSH Terms
-
- Humans
- Promoter Regions, Genetic
- Animals, Genetically Modified/genetics*
- Animals, Genetically Modified/growth & development
- Animals, Genetically Modified/metabolism
- Epistasis, Genetic*
- Zebrafish/genetics*
- Zebrafish/growth & development
- Zebrafish/metabolism
- Animals
- Regulatory Sequences, Nucleic Acid*
- Green Fluorescent Proteins/genetics
- Green Fluorescent Proteins/metabolism*
- Potassium Channels, Inwardly Rectifying/genetics
- Potassium Channels, Inwardly Rectifying/metabolism
- Gene Expression Regulation
- Transgenes*
- PubMed
- 27779464 Full text @ Zebrafish
Citation
Keefe, M.D., Bonkowsky, J.L. (2017) Transvection Arising from Transgene Interactions in Zebrafish. Zebrafish. 14(1):8-9.
Abstract
There has been a rapid expansion in use of transgenic technologies in zebrafish. We report a novel example of trans-interactions of genetic elements, or transvection. This interaction led to a novel expression pattern and illustrates a precautionary example regarding use of transgenes in zebrafish.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping