PUBLICATION
Quantitative methods for studying hemostasis in zebrafish larvae
- Authors
- Rost, M.S., Grzegorski, S.J., Shavit, J.A.
- ID
- ZDB-PUB-160618-12
- Date
- 2016
- Source
- Methods in cell biology 134: 377-89 (Chapter)
- Registered Authors
- Grzegorski, Steven, Rost, Megan, Shavit, Jordan
- Keywords
- Clotting, Coagulation, Fibrinogen, Hematology, Hemostasis, Thrombosis, Zebrafish
- MeSH Terms
-
- Animals
- Blood Coagulation/genetics*
- Hemostasis/genetics*
- Humans
- Larva/genetics
- Larva/physiology
- Thrombosis/genetics*
- Thrombosis/physiopathology
- Zebrafish/genetics
- Zebrafish/physiology
- PubMed
- 27312499 Full text @ Meth. Cell. Biol.
Citation
Rost, M.S., Grzegorski, S.J., Shavit, J.A. (2016) Quantitative methods for studying hemostasis in zebrafish larvae. Methods in cell biology. 134:377-89.
Abstract
Hemostasis is a coordinated system through which blood is prevented from exiting a closed circulatory system. We have taken advantage of the zebrafish, an emerging model for the study of blood coagulation, and describe three techniques for quantitative analysis of primary and secondary hemostasis. Collectively, these three techniques comprise a toolset to aid in our understanding of hemostasis and pathological clotting.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping