PUBLICATION

Zebrafish kidney development

Authors
Drummond, I.A., Davidson, A.J.
ID
ZDB-PUB-160618-11
Date
2016
Source
Methods in cell biology   134: 391-429 (Chapter)
Registered Authors
Davidson, Alan, Drummond, Iain
Keywords
Kidney, Nephron, Organogenesis, Pronephros, Regeneration
MeSH Terms
  • Animals
  • Gene Expression Regulation, Developmental
  • Humans
  • Kidney/growth & development*
  • Nephrons/growth & development
  • Organogenesis/genetics*
  • Pronephros/growth & development
  • Regeneration/genetics*
  • Zebrafish/genetics
  • Zebrafish/growth & development
PubMed
27312500 Full text @ Meth. Cell. Biol.
Abstract
The kidney of the zebrafish shares many features with other vertebrate kidneys including the human kidney. Similar cell types and shared developmental and patterning mechanisms make the zebrafish pronephros a valuable model for kidney organogenesis. Here we review recent advances in studies of zebrafish pronephric development and provide experimental protocols to analyze kidney cell types and structures, measure nephron function, live image kidney cells in vivo, and probe mechanisms of kidney regeneration after injury.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping