PUBLICATION
Data set in support of neurotoxicity of trimethyltin chloride by morphological and protein analysis
- Authors
- Kim, C.Y., Kim, J., Song, J., Oh, H., Park, J.H.
- ID
- ZDB-PUB-160310-5
- Date
- 2016
- Source
- Data in brief 6: 706-9 (Journal)
- Registered Authors
- Park, Jae-Hak
- Keywords
- Neurotoxicity, Trimethyltin chloride, Zebrafish
- MeSH Terms
- none
- PubMed
- 26958629 Full text @ Data Brief
Citation
Kim, C.Y., Kim, J., Song, J., Oh, H., Park, J.H. (2016) Data set in support of neurotoxicity of trimethyltin chloride by morphological and protein analysis. Data in brief. 6:706-9.
Abstract
Trimethyltin chloride (TMT) is a neurotoxicant widely present in the aquatic environment. Chronic exposure of embryos to TMT for 4 days post-fertilization (dpf) elicited a concentration-related decrease in head & eye size and increase in axial malformation. In addition, Rohon-Beard sensory neurons and motor neurons showed decreased patterns of protein expression. These data coincide with previous research about the neurotoxicity of TMT on mRNA expression (Kim et al., 2016 [1]). These data demonstrates that TMT inhibits specific neurodevelopmental stages in zebrafish embryos and suggests a possible mechanism for the toxicity of TMT in vertebrate neurodevelopment. This paper contains data related to research concurrently published in Kim et al. (2016) [1].
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping