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ZFIN ID: ZDB-PUB-150909-5
Development of social behavior in young zebrafish
Dreosti, E., Lopes, G., Kampff, A.R., Wilson, S.W.
Date: 2015
Source: Frontiers in neural circuits   9: 39 (Journal)
Registered Authors: Dreosti, Elena, Wilson, Steve
Keywords: NMDA receptors, ethanol, social behavior, visual behavior, zebrafish model system
MeSH Terms:
  • Age Factors
  • Aging*
  • Animals
  • Behavior, Animal/drug effects
  • Behavior, Animal/physiology*
  • Central Nervous System Depressants/pharmacology
  • Dizocilpine Maleate/pharmacology
  • Dose-Response Relationship, Drug
  • Ethanol/pharmacology
  • Excitatory Amino Acid Antagonists/pharmacology
  • Psychomotor Performance/drug effects
  • Social Behavior*
  • Zebrafish
PubMed: 26347614 Full text @ Front. Neural Circuits
Adult zebrafish are robustly social animals whereas larva is not. We designed an assay to determine at what stage of development zebrafish begin to interact with and prefer other fish. One week old zebrafish do not show significant social preference whereas most 3 weeks old zebrafish strongly prefer to remain in a compartment where they can view conspecifics. However, for some individuals, the presence of conspecifics drives avoidance instead of attraction. Social preference is dependent on vision and requires viewing fish of a similar age/size. In addition, over the same 1-3 weeks period larval zebrafish increasingly tend to coordinate their movements, a simple form of social interaction. Finally, social preference and coupled interactions are differentially modified by an NMDAR antagonist and acute exposure to ethanol, both of which are known to alter social behavior in adult zebrafish.