PUBLICATION
Next generation mothers: Maternal control of germline development in zebrafish
- Authors
- Dosch, R.
- ID
- ZDB-PUB-141123-5
- Date
- 2015
- Source
- Critical reviews in biochemistry and molecular biology 50(1): 54-68 (Review)
- Registered Authors
- Dosch, Roland
- Keywords
- Early embryogenesis, gamete, genetics, germ cell, germ plasm, maternal-effect, oocyte, oogenesis
- MeSH Terms
-
- Animals
- Male
- Mothers
- Female
- Embryo, Nonmammalian
- Zebrafish/embryology*
- Zebrafish/genetics
- Zebrafish/growth & development
- Oocytes/physiology*
- Gene Expression Regulation, Developmental*
- Oogenesis
- PubMed
- 25413788 Full text @ Crit. Rev. Biochem. Mol. Biol.
Citation
Dosch, R. (2015) Next generation mothers: Maternal control of germline development in zebrafish. Critical reviews in biochemistry and molecular biology. 50(1):54-68.
Abstract
Abstract In many animals, factors deposited by the mother into the egg control the earliest events in development of the zygote. These maternal RNAs and proteins play critical roles in oocyte development and the earliest steps of embryogenesis such as fertilization, cell division and embryonic patterning. Here, this article summarizes recent discoveries made on the maternal control of germline specification in zebrafish. Moreover, this review will discuss the major gaps remaining in our understanding of this process and highlight recent technical innovations in zebrafish, which allow tackling some of these questions in the near future.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping