ZFIN ID: ZDB-PUB-140707-2
Zebrafish as a model to explore cell metabolism
Santoro, M.M.
Date: 2014
Source: Trends in endocrinology and metabolism: TEM   25(10): 546-554 (Review)
Registered Authors: Santoro, Massimo
Keywords: drug screening, genetics, metabolic disorders, metabolomics, tools, zebrafish
MeSH Terms:
  • Animals
  • Cells/metabolism*
  • Humans
  • Models, Biological*
  • Zebrafish/genetics
  • Zebrafish/metabolism
PubMed: 24997878 Full text @ Trends Endocrinol. Metab.
Cell metabolism plays a key role in many essential biological processes. The recent availability of novel technologies and organisms to model cell metabolism in vivo is expanding current knowledge of cell metabolism. In this context, the zebrafish (Danio rerio) is emerging as a valuable model system to learn about the metabolic routes critical for cellular homeostasis. Here, the most recent methods and studies on cell metabolism are summarized, which support the overall value for the zebrafish model system not only to study metabolism but also metabolic disease states. It is envisioned that this small vertebrate system will help in the understanding of pathogenesis for numerous metabolic-related disorders in humans and in the identification of their therapeutic treatments.