Muller, F., and Tora, L. (2009) TBP2 is a general transcription factor specialized for female germ cells. Journal of biology. 8(11):97.
The complexity of the core promoter transcription machinery has emerged as an additional
level of transcription regulation that is used during vertebrate development. Recent
studies, including one published in BMC Biology, provide mechanistic insights into how the TATA binding protein (TBP) and its vertebrate-specific
paralog TBP2 (TRF3) switch function during the transition from the oocyte to the embryo.