PUBLICATION

Reverse genetics tools in zebrafish: A forward dive into endocrinology

Authors
Sugano, Y., and Neuhauss, S.C.
ID
ZDB-PUB-130322-1
Date
2013
Source
General and comparative endocrinology   188: 303-8 (Review)
Registered Authors
Neuhauss, Stephan, Sugano, Yuya
Keywords
zebrafish, reverse genetics, transgenesis
MeSH Terms
  • Animals
  • Animals, Genetically Modified
  • Endocrinology/methods*
  • Models, Animal
  • Reverse Genetics/methods*
  • Zebrafish*
PubMed
23454670 Full text @ Gen. Comp. Endocrinol.
Abstract

The zebrafish is a powerful genetic model organism. In recent years, zebrafish has been increasingly used to model human diseases. Due to a number of recent technological advancements, the genetic tool box is now also stocked with sophisticated transgenic and reverse genetic tools. Here, we focus on both commonly used and recently established reverse genetic and transgenic tools available in zebrafish. These new developments make the zebrafish an even more attractive animal model in comparative endocrinology.

Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping