Chun, H.S., Jeon, J.H., Pagire, H.S., Lee, J.H., Chung, H.C., Park, M.J., So, J.H., Ryu, J.H., Kim, C.H., Ahn, J.H., and Bae, M.A. (2013) Synthesis of LipidGreen2 and its application in lipid and fatty liver imaging. Molecular Biosystems. 9(4):630-633.
We have developed LipidGreen2, a second generation small molecule probe for lipid imaging. LipidGreen2 has a better fluorescence signal compared with the previous LipidGreen, and selectively stains neutral lipids in cells and fat deposits in live zebrafish. We also demonstrate the application of LipidGreen2 for detecting fatty liver.