PUBLICATION

Synthesis of LipidGreen2 and its application in lipid and fatty liver imaging

Authors
Chun, H.S., Jeon, J.H., Pagire, H.S., Lee, J.H., Chung, H.C., Park, M.J., So, J.H., Ryu, J.H., Kim, C.H., Ahn, J.H., and Bae, M.A.
ID
ZDB-PUB-130308-11
Date
2013
Source
Molecular Biosystems   9(4): 630-633 (Journal)
Registered Authors
Chun, Hang-Suk, Kim, Cheol-Hee, So, Ju-Hoon
Keywords
none
MeSH Terms
  • Animals
  • Cell Line
  • Fatty Liver/diagnosis*
  • Fluorescent Dyes/chemistry
  • Humans
  • Lipids/chemical synthesis
  • Lipids/chemistry*
  • Mice
  • Molecular Imaging*/methods
  • Molecular Probes/chemistry*
  • Zebrafish
PubMed
23412429 Full text @ Mol. Biosyst.
Abstract

We have developed LipidGreen2, a second generation small molecule probe for lipid imaging. LipidGreen2 has a better fluorescence signal compared with the previous LipidGreen, and selectively stains neutral lipids in cells and fat deposits in live zebrafish. We also demonstrate the application of LipidGreen2 for detecting fatty liver.

Genes / Markers
Figures
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Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes