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ZFIN ID: ZDB-PUB-130220-16
Anesthesia and euthanasia in zebrafish
Matthews, M., and Varga, Z.M.
Date: 2012
Source: ILAR journal   53(2): 192-204 (Review)
Registered Authors: Varga, Zoltan M.
Keywords: none
MeSH Terms:
  • Anesthetics*
  • Animals
  • Disease Models, Animal
  • Euthanasia*
  • Zebrafish
PubMed: 23382350 Full text @ ILAR (Institute for Laboratory Animal Research)

Because of the relative ease of embryonic manipulation and observation, the ability to produce a great number of genetic mutations, efficient screening methods, and the continued advance of molecular genetic tools, such as the progress in sequencing and mapping of the zebrafish genome, the use of zebrafish (Danio rerio) as a biomedical model organism continues to expand. However, studies involving zebrafish husbandry and veterinary care struggle to keep pace with scientific progress. This article outlines some of the current, acceptable methods for providing anesthesia and euthanasia and provides some examples of how performance-based approaches can be used to advance the relatively limited number of anesthetic and euthanizing techniques available for zebrafish.