PUBLICATION
Vertebrate Hedgehog signaling: cilia rule
- Authors
- Wilson, C.W., and Stainier, D.Y.
- ID
- ZDB-PUB-100811-1
- Date
- 2010
- Source
- BMC Biology 8: 102 (Review)
- Registered Authors
- Stainier, Didier
- Keywords
- none
- MeSH Terms
-
- Cilia/metabolism
- Carrier Proteins/metabolism
- Zebrafish
- Signal Transduction
- Hedgehog Proteins/metabolism*
- Animals
- Zebrafish Proteins/metabolism
- PubMed
- 20687907 Full text @ BMC Biol.
Citation
Wilson, C.W., and Stainier, D.Y. (2010) Vertebrate Hedgehog signaling: cilia rule. BMC Biology. 8:102.
Abstract
The Hedgehog (Hh) signaling pathway differentially utilizes the primary cilium in mammals and fruit flies. Recent work, including a study in BMC Biology, demonstrates that Hh signals through the cilium in zebrafish, clarifying the evolution of Hh signal transduction. See research article: http://www.biomedcentral.com/1741-7007/8/65.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping