PUBLICATION
Fly fishing for collective cell migration
- Authors
- Lopez-Schier, H.
- ID
- ZDB-PUB-100511-21
- Date
- 2010
- Source
- Current opinion in genetics & development 20(4): 428-432 (Review)
- Registered Authors
- Lopez-Schier, Hernan
- Keywords
- none
- MeSH Terms
-
- Animals
- Cell Movement/genetics*
- Cell Movement/physiology
- Drosophila/cytology*
- Drosophila/embryology
- Drosophila/genetics
- Drosophila Proteins/genetics
- Drosophila Proteins/physiology
- Embryo, Nonmammalian/cytology
- Embryo, Nonmammalian/metabolism
- Organogenesis/genetics
- Signal Transduction
- Zebrafish/embryology*
- Zebrafish/genetics
- Zebrafish Proteins/genetics
- Zebrafish Proteins/physiology
- PubMed
- 20452199 Full text @ Curr. Opin. Genet. Dev.
Citation
Lopez-Schier, H. (2010) Fly fishing for collective cell migration. Current opinion in genetics & development. 20(4):428-432.
Abstract
The collective migration of cells is essential for organogenesis. It requires the establishment of spatial information within the cellular group and a mechanism that controls the onset of cell movement and migratory arrest. In this review I will use two examples of collective cell migration, from Drosophila and the zebrafish, to discuss how genetic analyses have helped to unravel some basic aspects of collective cell migration. Following, I will suggest some general experimental approaches to further advance our understanding of the mechanisms that control the migration of cellular collectives.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping