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ZFIN ID: ZDB-PUB-100112-6
Myogenesis and molecules - insights from zebrafish Danio rerio
Chong, S.W., Korzh, V., and Jiang, Y.J.
Date: 2009
Source: Journal of Fish Biology   74(8): 1693-1755 (Review)
Registered Authors: Jiang, Yun-Jin, Korzh, Vladimir
Keywords: embryonic myogenesis, fast-twitch muscle, human, myofibril, slow-twitch muscle, zebrafish Danio rerio
MeSH Terms:
  • Animals
  • Chemokines/metabolism
  • Embryo, Nonmammalian/embryology
  • Fibroblast Growth Factors/metabolism
  • Homeodomain Proteins/metabolism
  • MicroRNAs/metabolism
  • Muscle Development/physiology*
  • Muscles/embryology*
  • Myoblasts/cytology
  • Myosins/metabolism
  • Protein Folding
  • Zebrafish/embryology*
PubMed: 20735668 Full text @ J. Fish Biol.
ABSTRACT
Myogenesis is a fundamental process governing the formation of muscle in multicellular organisms. Recent studies in zebrafish Danio rerio have described the molecular events occurring during embryonic morphogenesis and have thus greatly clarified this process, helping to distinguish between the events that give rise to fast v. slow muscle. Coupled with the well-known Hedgehog signalling cascade and a wide variety of cellular processes during early development, the continual research on D. rerio slow muscle precursors has provided novel insights into their cellular behaviours in this organism. Similarly, analyses on fast muscle precursors have provided knowledge of the behaviour of a sub-set of epitheloid cells residing in the anterior domain of somites. Additionally, the findings by various groups on the roles of several molecules in somitic myogenesis have been clarified in the past year. In this study, the authors briefly review the current trends in the field of research of D. rerio trunk myogenesis.
ADDITIONAL INFORMATION No data available