PUBLICATION
Adult neurogenesis in non-mammalian vertebrates
- Authors
- Chapouton, P., Jagasia, R., and Bally-Cuif, L.
- ID
- ZDB-PUB-091204-6
- Date
- 2007
- Source
- BioEssays : news and reviews in molecular, cellular and developmental biology 29(8): 745-757 (Review)
- Registered Authors
- Bally-Cuif, Laure, Chapouton, Prisca
- Keywords
- none
- MeSH Terms
-
- Adult Stem Cells/physiology*
- Animals
- Brain/cytology
- Brain/physiology*
- Cell Differentiation
- Cell Proliferation
- Models, Animal
- Models, Biological
- Nerve Regeneration/physiology*
- Neurons/physiology*
- Vertebrates
- PubMed
- 17621643 Full text @ Bioessays
Citation
Chapouton, P., Jagasia, R., and Bally-Cuif, L. (2007) Adult neurogenesis in non-mammalian vertebrates. BioEssays : news and reviews in molecular, cellular and developmental biology. 29(8):745-757.
Abstract
Adult neurogenesis is an exciting and rapidly advancing field of research. It addresses basic biological questions, such as the how and why of de novo neuronal production during adulthood, as well as medically relevant issues, including the potential link between adult neural stem cells and psychiatric disorders, or how stem cell manipulation might be used as a strategy for neuronal replacement. Current research mainly focuses on rodents, but we review here recent examination of non-mammalian vertebrates, which demonstrates that bona fide adult neural stem cells exist in these species. Importantly, especially in teleost fish, these cells can be abundant and located in various brain areas. Hence, non-mammalian vertebrate species provide invaluable comparative material for extracting core mechanisms of adult neural stem cell maintenance and fate.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping