PUBLICATION
Evolution of class I cytokine receptor signalling : conservation of GCSFR
- Authors
- Liongue, C.
- ID
- ZDB-PUB-090521-145
- Date
- 2008
- Source
- Ph.D. Thesis : 249p (Thesis)
- Registered Authors
- Liongue, Clifford
- Keywords
- cytokines, physiological effect, granulocytes, cellular signal transduction
- MeSH Terms
- none
- PubMed
- none
Citation
Liongue, C. (2008) Evolution of class I cytokine receptor signalling : conservation of GCSFR. Ph.D. Thesis. :249p.
Abstract
Cytokines are proteins that provide essential signals to blood and immune cells. The evolution of this system was determined from primitive organisms to humans and zebrafish. Analysis of zebrafish granulocyte colony-stimulating factor (GCSF) signalling revealed broad conservation of function with mammals and a novel role in white blood cell migration.
Errata / Notes
Ph.D. Thesis, Deakin University, Victoria
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping