PUBLICATION

Evolution of class I cytokine receptor signalling : conservation of GCSFR

Authors
Liongue, C.
ID
ZDB-PUB-090521-145
Date
2008
Source
Ph.D. Thesis : 249p (Thesis)
Registered Authors
Liongue, Clifford
Keywords
cytokines, physiological effect, granulocytes, cellular signal transduction
MeSH Terms
none
PubMed
none
Abstract
Cytokines are proteins that provide essential signals to blood and immune cells. The evolution of this system was determined from primitive organisms to humans and zebrafish. Analysis of zebrafish granulocyte colony-stimulating factor (GCSF) signalling revealed broad conservation of function with mammals and a novel role in white blood cell migration.
Errata / Notes
Ph.D. Thesis, Deakin University, Victoria
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping