PUBLICATION
Gene regulation technologies in zebrafish
- Authors
- Esengil, H., and Chen, J.K.
- ID
- ZDB-PUB-080327-5
- Date
- 2008
- Source
- Molecular Biosystems 4(4): 300-308 (Review)
- Registered Authors
- Chen, James K.
- Keywords
- none
- MeSH Terms
-
- Animals
- Gene Expression Regulation/physiology*
- Genetic Engineering*
- Zebrafish/genetics*
- Zebrafish/metabolism*
- Zebrafish Proteins/genetics
- Zebrafish Proteins/metabolism
- PubMed
- 18354783 Full text @ Mol. Biosyst.
Citation
Esengil, H., and Chen, J.K. (2008) Gene regulation technologies in zebrafish. Molecular Biosystems. 4(4):300-308.
Abstract
Achieving the potential of zebrafish models in biomedical research is contingent on the development of reverse-genetic resources. This review describes current technologies for genetic perturbations in zebrafish, including an ecdysone receptor-based system that permits conditional transgene expression. Such methodologies promise to enable new zebrafish models for interrogating human physiology and disease.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping