|ZFIN ID: ZDB-PUB-071016-1|
Sp1-like transcription factors are regulators of embryonic development in vertebrates
Zhao, C., and Meng, A.
|Source:||Development, growth & differentiation 47(4): 2001-211 (Review)|
|Registered Authors:||Meng, Anming, Zhao, Chengtian|
|PubMed:||15921495 Full text @ Dev. Growth Diff.|
Zhao, C., and Meng, A. (2005) Sp1-like transcription factors are regulators of embryonic development in vertebrates. Development, growth & differentiation. 47(4):2001-211.
ABSTRACTSp1-like family is an expanding transcription factor family. Members of this family bind to the GC-box or GT-box elements in the promoter/enhancers and regulate the expression of the target genes. Currently, this family consists of at least nine members, which may act as a transactivator or a repressor on target promoters. Sp1-like transcription factors are expressed during development of vertebrate embryos in ubiquitous or tissue-specific manners and play various roles in embryonic development. This review mainly summarises their expression patterns and functions during vertebrate embryogenesis.
ADDITIONAL INFORMATION No data available