PUBLICATION
Peripheral glia: Schwann cells in motion
- Authors
- Lai, C.
- ID
- ZDB-PUB-050513-9
- Date
- 2005
- Source
- Current biology : CB 15(9): R332-334 (Review)
- Registered Authors
- Keywords
- none
- MeSH Terms
-
- Animals
- Axons/physiology*
- Cell Movement/physiology*
- Cell Proliferation*
- Mutation/genetics
- Myelin Sheath/metabolism*
- Neuregulins/metabolism*
- Receptor, ErbB-2/genetics
- Receptor, ErbB-2/metabolism
- Schwann Cells/metabolism
- Schwann Cells/physiology*
- Signal Transduction/physiology*
- Zebrafish
- PubMed
- 15886089 Full text @ Curr. Biol.
Citation
Lai, C. (2005) Peripheral glia: Schwann cells in motion. Current biology : CB. 15(9):R332-334.
Abstract
Neuregulin signaling through ErbB receptors is known to play an essential role in Schwann cell proliferation, survival and myelination. Recent studies in zebrafish provide a peek at living Schwann cells migrating along axons in vivo and suggest that ErbB signaling, while not required for cell movement per se, is required to maintain the directed migration of these cells.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping