PUBLICATION
Expression of bmp2a and bmp2b in late-stage zebrafish median fin development
- Authors
- Crotwell, P.L., Sommervold, A.R., and Mabee, P.M.
- ID
- ZDB-PUB-041130-14
- Date
- 2004
- Source
- Gene expression patterns : GEP 5(2): 291-296 (Journal)
- Registered Authors
- Crotwell, Patricia, Mabee, Paula M.
- Keywords
- Zebrafish; bmp2; bmp2a; bmp2b; Median fins; Radials; Hypurals; Fin rays; Neural and hemal arches; Neural and hemal spines; Lens; Cartilage; Segmentation; RT-PCR; In situ hybridization
- MeSH Terms
-
- Larva/growth & development
- Larva/metabolism
- Gene Expression Regulation, Developmental
- Bone Morphogenetic Proteins/metabolism*
- Extremities/growth & development
- RNA, Messenger/biosynthesis
- Bone Morphogenetic Protein 2
- Zebrafish/anatomy & histology
- Zebrafish/growth & development
- Zebrafish/metabolism*
- Animals
- Chondrocytes/metabolism
- Zebrafish Proteins/biosynthesis*
- Zebrafish Proteins/metabolism
- PubMed
- 15567728 Full text @ Gene Expr. Patterns
Citation
Crotwell, P.L., Sommervold, A.R., and Mabee, P.M. (2004) Expression of bmp2a and bmp2b in late-stage zebrafish median fin development. Gene expression patterns : GEP. 5(2):291-296.
Abstract
Zebrafish bmp2a and bmp2b mRNA expression in the developing median fins (caudal, anal, and dorsal) of late-stage larvae (>5 days post-fertilization) was analyzed by reverse transcriptase-PCR (RT-PCR) and in situ hybridization. bmp2a is expressed in developing fin rays, while bmp2b is expressed in developing fin rays, hypertrophic chondrocytes, and in the zone of segmentation (ZS) in developing anal and dorsal fin radials. This latter pattern of bmp2b expression in the ZS mirrors tetrapod bmp2 expression in developing joints. Additionally, both genes are expressed in neural and hemal arches and spines. bmp2a is strongly expressed in the lens; lens bmp2b expression is detected only weakly via RT-PCR.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping