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ZFIN ID: ZDB-PUB-031229-11
Using the adult zebrafish visual system to study cadherin-2 expression during central nervous system regeneration
Liu, Q. and Londraville, R.L.
Date: 2003
Source: Methods in cell science : an official journal of the Society for In Vitro Biology 25(1-2): 71-78 (Review)
Registered Authors: Liu, Qin
Keywords: cell adhesion molecules, optic pathway, regeneration, retina, zebrafish
MeSH Terms:
  • Animals
  • Brain/metabolism
  • Cadherins/metabolism*
  • Eye/metabolism*
  • Eye/physiopathology
  • Nerve Regeneration/physiology*
  • Optic Nerve/metabolism
  • Optic Nerve/physiology
  • Retina/metabolism*
  • Zebrafish/metabolism*
PubMed: 14739590 Full text @ Methods Cell Sci.
Zebrafish is a good model organism for the study of vertebrate development due to numerous experimental advantages. Here we show that zebrafish are also suitable for the study of cellular and molecular mechanisms underlying tissue regeneration in the vertebrate central nervous system. In this report we describe simple protocols to introduce injuries to the adult zebrafish visual structures and analyze cadherin-2 expression in the regenerating visual system using immunocytochemistry and immunoblotting.