PUBLICATION
The guts of endoderm formation
- Authors
- Warga, R.M. and Stainier, D.Y.R.
- ID
- ZDB-PUB-030425-8
- Date
- 2002
- Source
- Results and problems in cell differentiation 40: 28-47 (Review)
- Registered Authors
- Stainier, Didier, Warga, Rachel M.
- Keywords
- none
- MeSH Terms
-
- Zebrafish/embryology*
- Endoderm/metabolism*
- Endoderm/physiology*
- Transcription, Genetic
- Signal Transduction
- Gene Expression Regulation, Developmental
- Stem Cells
- Blastula/physiology*
- Animals
- Models, Biological
- Mesoderm/physiology
- PubMed
- 12353482 Full text @ Results Probl. Cell Diff.
Citation
Warga, R.M. and Stainier, D.Y.R. (2002) The guts of endoderm formation. Results and problems in cell differentiation. 40:28-47.
Abstract
In this chapter, we will review the formation of the definitive endoderm , the population of cells that give rise to the lining of the digestive tract, its associated organs and the pharyngeal pouches. At the cellular level, we will describe the location and movement of endodermal cells from the onset of epiboly until the end of gastrulation. At the molecular level, we will discuss the genes associated with endoderm formation beginning with Nodal signaling. For convenience, we use the term involution, sometimes referred to as internalization; we also separate endoderm formation into the pre-involution (blastula) and post- involution (gastrula) periods although of course endoderm formation involves a continuous series of events. In addition, we refer to the cells that contribute to the endoderm as progenitors prior to their involution and precursors after their involution.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping