|ZFIN ID: ZDB-PUB-010219-15|
The zebrafish Hairy/Enhancer-of-split-related gene her6 is segmentally expressed during the early development of hindbrain and somites
Pasini, A., Henrique, D., and Wilkinson, D.G.
|Source:||Mechanisms of Development 100(2): 317-321 (Journal)|
|Registered Authors:||Wilkinson, David|
|Keywords:||zebrafish; embryogenesis; central nervous system; hindbrain; rhombomeres; segmentation; boundaries; Hairy/Enhancer-of-split genes; her genes; her6; krox20; bHLH proteins; somitogenesis; presomitic mesoderm; somites|
|PubMed:||11165489 Full text @ Mech. Dev.|
Pasini, A., Henrique, D., and Wilkinson, D.G. (2001) The zebrafish Hairy/Enhancer-of-split-related gene her6 is segmentally expressed during the early development of hindbrain and somites. Mechanisms of Development. 100(2):317-321.
ABSTRACTSeveral vertebrate genes of the Hairy/Enhancer-of-split (HES) family are involved in paraxial mesoderm segmentation and intersomitic boundary establishment/maintenance. Here, we show that the zebrafish hairy-related gene, her6, highly homologous to the mammalian and chicken HES-1 genes, is expressed in the posterior part of each segmented somite and in stripes in the anterior presomitic mesoderm (PSM), and also in a dynamic, segmentally restricted pattern during hindbrain segmentation, with all rhombomeres expressing her6 at different time points and at different levels.
- Genes / Markers (2)