|ZFIN ID: ZDB-PUB-001205-9|
Zebrafish Hsp40 and Hsc70 genes are both induced during caudal fin regeneration
Tawk, M., Joulie, C., and Vriz, S.
|Source:||Mechanisms of Development 99(1-2): 183-186 (Journal)|
|Registered Authors:||Vriz, Sophie|
|Keywords:||zebrafish; caudal fin; regeneration; development; Hsp40; wound healing; blastema; chaperones; Hsc70; heat shock proteins; osteoblasts|
|PubMed:||11091090 Full text @ Mech. Dev.|
Tawk, M., Joulie, C., and Vriz, S. (2000) Zebrafish Hsp40 and Hsc70 genes are both induced during caudal fin regeneration. Mechanisms of Development. 99(1-2):183-186.
ABSTRACTWe report the characterization of a zebrafish DnaJ-like protein, homologue to the human Hsp40 protein hdj1, that we named zf-Hsp40. We have studied its expression during fin regeneration and we show that zf-Hsp40 mRNA level is drastically increased in all ray segments beneath the regenerated part, or blastema, in response to caudal fin amputation. In order to investigate whether zf-Hsp40 is part of a stress response system after injury, we studied the expression of the zebrafish Hsc70 transcript. Our results show a correlation between the expression of the two transcripts.
- Genes / Markers (1)