| ZFIN ID: ZDB-PUB-001205-9 |
Zebrafish Hsp40 and Hsc70 genes are both induced during caudal fin regeneration
Tawk, M., Joulie, C., and Vriz, S.
| Date: | 2000 |
|---|---|
| Source: | Mechanisms of Development 99(1-2): 183-186 (Journal) |
| Registered Authors: | Vriz, Sophie |
| Keywords: | zebrafish; caudal fin; regeneration; development; Hsp40; wound healing; blastema; chaperones; Hsc70; heat shock proteins; osteoblasts |
| MeSH Terms: |
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| PubMed: | 11091090 Full text @ Mech. Dev. |
Citation
Tawk, M., Joulie, C., and Vriz, S. (2000) Zebrafish Hsp40 and Hsc70 genes are both induced during caudal fin regeneration. Mechanisms of Development. 99(1-2):183-186.
ABSTRACT
We report the characterization of a zebrafish DnaJ-like protein, homologue to the human Hsp40 protein hdj1, that we named zf-Hsp40. We have studied its expression during fin regeneration and we show that zf-Hsp40 mRNA level is drastically increased in all ray segments beneath the regenerated part, or blastema, in response to caudal fin amputation. In order to investigate whether zf-Hsp40 is part of a stress response system after injury, we studied the expression of the zebrafish Hsc70 transcript. Our results show a correlation between the expression of the two transcripts.
ADDITIONAL INFORMATION
- Genes / Markers (1)