PUBLICATION
Vertebrate development: The fast track to Nodal signalling
- Authors
- Stemple, D.L.
- ID
- ZDB-PUB-001205-2
- Date
- 2000
- Source
- Current biology : CB 10(22): R843-R846 (Review)
- Registered Authors
- Stemple, Derek L.
- Keywords
- none
- MeSH Terms
-
- Mutagenesis
- Nodal Protein
- GPI-Linked Proteins
- Transforming Growth Factor beta/metabolism*
- Transforming Growth Factor beta/physiology
- Xenopus Proteins*
- Signal Transduction/physiology*
- DNA-Binding Proteins/genetics
- DNA-Binding Proteins/metabolism
- DNA-Binding Proteins/physiology*
- Animals
- Transcription Factors/genetics
- Transcription Factors/metabolism
- Transcription Factors/physiology*
- Intercellular Signaling Peptides and Proteins
- Homeodomain Proteins/genetics
- Homeodomain Proteins/metabolism
- Homeodomain Proteins/physiology*
- Forkhead Transcription Factors
- Zebrafish/embryology*
- Zebrafish Proteins*
- PubMed
- 11102828 Full text @ Curr. Biol.
Citation
Stemple, D.L. (2000) Vertebrate development: The fast track to Nodal signalling. Current biology : CB. 10(22):R843-R846.
Abstract
The transcription factors Fast-1 and Mixer are important terminal components of Smad2-mediated TGF-beta signal transduction. Recent studies demonstrate that Fast-1 and Mixer play critical roles in the formation of endoderm and dorsal mesoderm in zebrafish.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping