Stemple, D.L. (2000) Vertebrate development: The fast track to Nodal signalling. Current biology : CB. 10(22):R843-R846.
The transcription factors Fast-1 and Mixer are important terminal components of Smad2-mediated TGF-beta signal transduction. Recent studies demonstrate that Fast-1 and Mixer play critical roles in the formation of endoderm and dorsal mesoderm in zebrafish.