|ZFIN ID: ZDB-PUB-000111-4|
Sequence and embryonic expression of deltaC in the zebrafish
Smithers, L., Haddon, C., Jiang, Y.J., and Lewis, J.
|Source:||Mechanisms of Development 90(1): 119-123 (Journal)|
|Registered Authors:||Haddon, Catherine, Jiang, Yun-Jin, Lewis, Julian|
|Keywords:||zebrafish; Delta; Notch; X-Delta-2; deltaA, deltaB, deltaC, deltaD; notch1a; pax2.1; vegr-2; germ ring; tailbud; somites; neural tube; ear, retina; lateral line; cranial ganglia; notochord; aorta; endothelium; pronephros; epidermis|
|PubMed:||10585570 Full text @ Mech. Dev.|
Smithers, L., Haddon, C., Jiang, Y.J., and Lewis, J. (2000) Sequence and embryonic expression of deltaC in the zebrafish. Mechanisms of Development. 90(1):119-123.
ABSTRACTFour genes - deltaA, deltaB, deltaC and deltaD - coding for homologues of the Notch ligand Delta have been discovered in zebrafish (Haddon et al., 1998b). We report here the cDNA sequence and expression pattern of deltaC. Its closest relatives are deltaB and Xenopus X-Delta-2. Unlike deltaA, deltaB, and deltaD, deltaC is not expressed in the majority of nascent primary neurons; but it is strongly expressed in the early retina, where it precedes other delta genes. It is also expressed in cranial ganglia, in sensory epithelia including ear and lateral line, and in scattered epidermal cells. In the mesoderm, expression is visible by 50% epiboly; it is seen subsequently in the tail bud, in stripes in the presomitic mesoderm and in the posterior half of each somite. There is expression also in notochord, blood vessels and pronephros.
- Genes / Markers (7)