ZFIN ID: ZDB-PERS-970424-35
Sharrocks, Andrew D.
Email: a.d.sharrocks@manchester.ac.uk
URL: http://www.ncl.ac.uk/~nbiochem/sharrock.html
Affiliation: Sharrocks Lab
Address: School of Biological Sciences Manchester University 2.205 Stopford Building Oxford Road Manchester, M13 9PT United Kingdom
Country: United Kingdom
Phone: 44-161-275-5979
Fax: 44-161-275-5082

Research interests- The group is studying several aspects of eukaryotic transcriptional regulation. We are using zebrafish as a model system to investigate several aspects of this subject. In particular, we have isolated three cDNAs and are currently studying the functions of the encoded zebrafish ETS-domain transcription factors.

Gerrard, D.T., Berry, A.A., Jennings, R.E., Birket, M.J., Zarrineh, P., Garstang, M.G., Withey, S.L., Short, P., Jiménez-Gancedo, S., Firbas, P.N., Donaldson, I., Sharrocks, A.D., Hanley, K.P., Hurles, M.E., Gomez-Skarmeta, J.L., Bobola, N., Hanley, N.A. (2020) Dynamic changes in the epigenomic landscape regulate human organogenesis and link to developmental disorders. Nature communications. 11:3920
Brown, L.A., Rodaway, A.R.F., Schilling, T.F., Jowett, T., Ingham, P.W., Patient, R.K., and Sharrocks, A.D. (2000) Insights into early vasculogenesis revealed by expression of the ETS-domain transcription factor Fli-1 in wild-type and mutant zebrafish embryos. Mechanisms of Development. 90(2):237-252
Brown, L.A., Yang, S.H., Hair, A., Galanis, A., and Sharrocks, A.D. (1999) Molecular characterization of a zebrafish TCF ETS-domain transcription factor. Oncogene. 18(56):7985-7993
Brown, L.A., Amores, A., Schilling, T.F., Jowett, T., Baert, J.L., De Launoit, Y., and Sharrocks, A.D. (1998) Molecular characterization of the zebrafish PEA3 ETS-domain transcription factor. Oncogene. 17:93-104