ZFIN ID: ZDB-PERS-960905-4 |
Clark, Karl
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BIOGRAPHY AND RESEARCH INTERESTS
My research interests are focused on applying molecular and genetic tools to dissect and discover the interactions between genes and the environment that affect both short and long-term changes in physiology and behavior. In particular, I am interested in the bridge between genes and environment that is gated by the stress response- with a focus on addiction.
PUBLICATIONS
NON-ZEBRAFISH PUBLICATIONS
Hyland, K.A., Olson, E.R., Clark, K.J., Aronovich, E.L., Hackett, P.B., Blazer, B.R., Tolar, J.*, and McIvor, R.S.* (2011) Sleeping Beauty-mediated correction of Fanconi anemia type C. Journal of Gene Medicine 13: 462-469.
Carlson, D.F., Garbe, J.R., Wenfang, T., Martin, M.J., Dobrinsky, J.R., Hackett, P.B., Clark, K.J. and Fahrenkrug, S.C. (2011) Strategies for selection marker-free swine transgenesis using the Sleeping Beauty transposon system. Transgenic Research.
Garbe, J.R., Elsik, C.G., Antoniou, E., Reecy, J.M., Clark, K.J., Venkatraman, A., Kim, J-W., Schnabel, R.D., Dickens, C.M., Wolfinger, R.D., Fahrenkrug, S.C. and Taylor, J.F. (2010) Development and application of bovine and porcine oligonucleotide arrays with protein based annotation. J Biomed and Biotechnol 2010:453638
Clark, K.J., Leaver, M.J., Foster, L.K., Carlson, D.F., and Fahrenkrug, S.C. (2009) Passport, a native Tc1/mariner transposon from a flatfish, is functionally active in vertebrate cells. Nucleic Acids Research 37(4):1239-47. Epub 2009 Jan 9. PMC2651795
Ni, J., Clark, K.J., Fahrenkrug, S.C., and Ekker, S.C. (2008). Transposon tools hopping in vertebrates. Brief Funct Genomic Proteomic 7:444-53. PMC2722259
Clark, K.J.*, Carlson, D.F.*, and Fahrenkrug, S.C. (2007) Pigs taking wing with transposons and recombinases. Genome Biology 8(Suppl 1):S13. PMC2106845
Clark, K.J., Carlson, D.F., Foster, L.K., Kong, B.W., Foster, D.N., and Fahrenkrug, S.C. (2007). Enzymatic engineering of the porcine genome with transposons and recombinases. BMC Biotechnol 7:42. PMC1939997
Geurts, A.M, Wilbur, A., Carlson, C.M., Lobitz, P.D., Clark, K.J., Hackett, P.B., McIvor, R.S., and Largaespada, D.A. (2006) Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon. BMC Biotechnol 6:30. PMC1557845
Wadman, S.A., Clark, K.J. and Hackett, P.B. (2005) Fishing for answers with transposons. Mar. Biotech 7:135-141.
Ohlfest, J.R., Frandsen, J.L., Fritz, S., Lobitz, P.D., Perkinson, S.G., Clark, K.J., Nelsestuen, G., Key, N.S., McIvor, R.S., Hackett, P.B., and Largaespada, D.A. (2005) Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system. Blood 105:2691-2698.
Geurts, A.M., Yang, Y., Clark, K.J., Liu, G., Cui, Z., Dupuy, A.J., Bell, J.B., Largaespada, D.A., and Hackett, P.B. (2003) Gene transfer into genomes of human cells by the sleeping beauty transposon system. Mol Ther 8:108-17.
*Authors Contributed Equally.