ZFIN ID: ZDB-PERS-960805-76
Brownlie, Alison J.
Email: Abrownlie@xenongenetics.com
URL:
Affiliation:
Address: Xenon Genetics Inc. 2386 East Mall, Suite 101 Vancouver, V6T 1Z3 Canada
Country:
Phone: (604) 221-8478
Fax: (604) 221-8423
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BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Shaw, G.C., Cope, J.J., Li, L., Corson, K., Hersey, C., Ackermann, G.E., Gwynn, B., Lambert, A.J., Wingert, R.A., Traver, D., Trede, N.S., Barut, B.A., Zhou, Y., Minet, E., Donovan, A., Brownlie, A., Balzan, R., Weiss, M.J., Peters, L.L., Kaplan, J., Zon, L.I., and Paw, B.H. (2006) Mitoferrin is essential for erythroid iron assimilation. Nature. 440(7080):96-100
Wingert, R.A., Brownlie, A., Galloway, J.L., Dooley, K., Fraenkel, P., Axe, J.L., Davidson, A.J., Barut, B., Noriega, L., Sheng, X., Zhou, Y., Tübingen 2000 Screen Consortium, and Zon, L.I. (2004) The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1. Development (Cambridge, England). 131(24):6225-6235
Paw, B.H., Davidson, A.J., Zhou, Y., Li, R., Pratt, S.J., Lee, C., Trede, N.S., Brownlie, A., Donovan, A., Liao, E.C., Ziai, J.M., Drejer, A.H., Guo, W., Kim, C.H., Gwynn, B., Peters, L.L., Chernova, M.N., Alper, S.L., Zapata, A., Wickramasinghe, S.N., Lee, M.J., Lux, S.E., Fritz, A., Postlethwait, J.H., and Zon, L.I. (2003) Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nature Genetics. 34(1):59-64
Brownlie, A., Hersey, C., Oates, A.C., Paw, B.H., Falick, A.M., Witkowska, H.E., Flint,J., Higgs, D., Jessen, J., Bahary, N., Zhu, H., Lin, S. and Zon, L. (2003) Characterization of embryonic globin genes of the zebrafish. Developmental Biology. 255(1):48-61
Donovan, A., Brownlie, A., Dorschner, M., Zhou, Y., Pratt, S.J., Paw, B.H., Thisse, C., Thisse, B., and Zon, L.I. (2002) The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1). Blood. 100:4655-4659
Pratt, S.J., Drejer, A., Foott, H., Barut, B., Brownlie, A., Postlethwait, J., Kato, Y., Yamamoto, M., and Zon, L.I. (2002) Isolation and characterization of zebrafish NFE2. Physiological Genomics. 11(2):91-98
Paw, B.H., Zhou, Y., Li, R., Pratt, S.J., Davidson, A.J., Trede, N.S., Brownlie, A., Donovan, A., Liao, E.C., Drejer, A., Peters, L.L., Gwynn, B., Lux, S.E., and Zon, L.I. (2000) Cloning of the zebrafish Retsina blood mutation: Mutations in erythroid band 3 result in dyserythropoiesis and cytokinesis defects. Blood. 96(11):1895
Donovan, A., Brownlie, A., Zhou, Y., Shepard, J., Pratt, S.J., Moynihan, J., Paw, B.H., Drejer, A., Barut, B., Zapata, A., Law, T.C., Brugnara, C., Lux, S.E., Pinkus, G.S., Pinkus, J.L., Kingsley, P.D., Palis, J., Fleming, M.D., Andrews, N.C., and Zon, L.I. (2000) Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature. 403(6771):776-781
Oates, A.C., Brownlie, A., Pratt, S.J., Irvine, D.V., Liao, E.C., Paw, B.H., Dorian, K.J., Johnson, S.L., Postlethwait, J.H., Zon, L.I., and Wilks, A.F. (1999) Gene duplication of zebrafish JAK2 homologs is accompanied by divergent embryonic expresssion patterns: only jak2a is expressed during erythropoiesis. Blood. 94(8):2622-2636
Brownlie, A. and Zon, L. (1999) The zebrafish as a model system for the study of hematopoiesis. Bioscience. 49(5):382-392
Brownlie, A.J. (1999) Characterization of the hypochromic blood mutants zinfandel, chianti and sauternes: a genetic analysis of hemoglobin synthesis in the zebrafish, Danio rerio. Ph.D. Thesis.
Brownlie, A., Donovan, A., Pratt, S.J., Paw, B.H., Oates, A.C., Brugnara, C., Witkowska, H.E., Sassa, S., and Zon, L.I. (1998) Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia. Nature Genetics. 20:244-250
Thompson, M.A., Ransom, D.G., Pratt, S.J., MacLennan, H., Kieran, M.W., Detrich,III, H.W., Vail, B., Huber, T.L., Paw, B., Brownlie, A.J., Oates, A.C., Fritz, A., Gates, MA., Amores, A., Bahary, N., Talbot, W.S., Her, H., Beier, D.R., Postlethwait, J.H., and Zon, L.I. (1998) The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis. Developmental Biology. 197:248-269
Postlethwait, J.H, Yan, Y.-L., Gates, M.A., Horne, S., Amores, A., Brownlie, A., Donovan, A., Egan, E.S., Force, A., Gong, Z., Goutel, C., Fritz, A., Kelsh, R., Knapik, E., Liao, E., Paw, B., Ransom, D., Singer, A., Thomson, M., Abduljabbar, T.S., Yelick, P., Beier, D., Joly, J.-S., Larhammar, D., Rosa, F., Westerfield, M., Zon, L.I., Johnson, S.L., and Talbot, W.S. (1998) Vertebrate genome evolution and the zebrafish gene map. Nature Genetics. 18:345-349
Chan, F.Y., Robinson, J., Brownlie, A., Shivdasani, R.A., Donovan, A., Brugnara, C., Kim, J., Lau, B.C., Witkowska, H.E., and Zon, L.I. (1997) Characterization of adult alpha- and beta-globin genes in the zebrafish. Blood. 89(2):688-700
Ransom, D.G., Haffter, P., Odenthal, J., Brownlie, A., Vogelsang, E., Kelsh, R.N., Brand, M., van Eeden, F.J., Furutani-Seiki, M., Granato, M., Hammerschmidt, M., Heisenberg, C.P., Jiang, Y.J., Kane, D.A., Mullins, M.C., and Nüsslein-Volhard, C. (1996) Characterization of zebrafish mutants with defects in embryonic hematopoiesis. Development (Cambridge, England). 123:311-319
Zon, L.I., Kieran, M., Paw, B., Thompson, M., Guo, W., Ransom, D., Brownlie, A., Chan, F.Y., Barone, L., McClennan, H., Ziegler, S., Pratt, S., and Detrich, H.W. III (1995) The zebrafish: a new model for studying embryonic hematopoiesis. In Ontogeny of hematopoiesis. Aplastic anemia, E. Gluckman, L. Coulombel, eds., Paris: Colloque INSERM/John Libbey Eurotext. 235:17-22

NON-ZEBRAFISH PUBLICATIONS