ZFIN ID: ZDB-PERS-960805-500
Schier, Alexander
Email: schier@mcb.harvard.edu
URL: http://www.mcb.harvard.edu/Faculty/Schier.html
Affiliation: Schier Lab
Address: Harvard University Department of Molecular and Cellular Biology 16 Divinity Avenue Cambridge, MA 02138 USA
Country: United States
Phone: 617-496-4845
Fax: 617-495-9300
Orcid ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Freyer, L., Hsu, C.W., Nowotschin, S., Pauli, A., Ishida, J., Kuba, K., Fukamizu, A., Schier, A.F., Hoodless, P.A., Dickinson, M.E., Hadjantonakis, A.K. (2017) Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives. Cell Reports. 20:2116-2130
Hildebrand, D.G.C., Cicconet, M., Torres, R.M., Choi, W., Quan, T.M., Moon, J., Wetzel, A.W., Scott Champion, A., Graham, B.J., Randlett, O., Plummer, G.S., Portugues, R., Bianco, I.H., Saalfeld, S., Baden, A.D., Lillaney, K., Burns, R., Vogelstein, J.T., Schier, A.F., Lee, W.A., Jeong, W.K., Lichtman, J.W., Engert, F. (2017) Whole-brain serial-section electron microscopy in larval zebrafish. Nature. 545(7654):345-349
McKenna, A., Findlay, G.M., Gagnon, J.A., Horwitz, M.S., Schier, A.F., Shendure, J. (2016) Whole organism lineage tracing by combinatorial and cumulative genome editing. Science (New York, N.Y.). 353(6298):aaf7907
Thyme, S.B., Akhmetova, L., Montague, T.G., Valen, E., Schier, A.F. (2016) Internal guide RNA interactions interfere with Cas9-mediated cleavage. Nature communications. 7:11750
Chew, G.L., Pauli, A., Schier, A.F. (2016) Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish. Nature communications. 7:11663
Thyme, S.B., Schier, A.F. (2016) Correction: Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development. Cell Reports. 15:1611-1613
Thyme, S.B., Schier, A.F. (2016) Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development. Cell Reports.
Dunn, T.W., Mu, Y., Narayan, S., Randlett, O., Naumann, E.A., Yang, C.T., Schier, A.F., Freeman, J., Engert, F., Ahrens, M.B. (2016) Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion. eLIFE. 5:e12741
Chiu, C.N., Rihel, J., Lee, D.A., Singh, C., Mosser, E.A., Chen, S., Sapin, V., Pham, U., Engle, J., Niles, B.J., Montz, C.J., Chakravarthy, S., Zimmerman, S., Salehi-Ashtiani, K., Vidal, M., Schier, A.F., Prober, D.A. (2016) A Zebrafish Genetic Screen Identifies Neuromedin U as a Regulator of Sleep/Wake States. Neuron. 89:842-856
Haesemeyer, M., Robson, D.N., Li, J.M., Schier, A.F., Engert, F. (2015) The structure and timescales of heat perception in larval zebrafish. Cell systems. 1:338-348
Randlett, O., Wee, C.L., Naumann, E.A., Nnaemeka, O., Schoppik, D., Fitzgerald, J.E., Portugues, R., Lacoste, A.M., Riegler, C., Engert, F., Schier, A.F. (2015) Whole-brain activity mapping onto a zebrafish brain atlas. Nature Methods. 12:1039-1046
Pauli, A., Montague, T.G., Lennox, K.A., Behlke, M.A., Schier, A.F. (2015) Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish. PLoS One. 10:e0139504
Mundell, N.A., Beier, K.T., Pan, Y.A., Lapan, S.W., Göz Aytürk, D., Berezovskii, V.K., Wark, A.R., Drokhlyansky, E., Bielecki, J., Born, R.T., Schier, A.F., Cepko, C.L. (2015) Vesicular stomatitis virus enables gene transfer and transsynaptic tracing in a wide range of organisms. The Journal of comparative neurology. 523(11):1639-63
Li-Villarreal, N., Forbes, M.M., Loza, A.J., Chen, J., Ma, T., Helde, K., Moens, C.B., Shin, J., Sawada, A., Hindes, A.E., Dubrulle, J., Schier, A.F., Longmore, G.D., Marlow, F.L., Solnica-Krezel, L. (2015) Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development (Cambridge, England). 142(15):2704-18
Lacoste, A.M., Schoppik, D., Robson, D.N., Haesemeyer, M., Portugues, R., Li, J.M., Randlett, O., Wee, C.L., Engert, F., Schier, A.F. (2015) A Convergent and Essential Interneuron Pathway for Mauthner-Cell-Mediated Escapes. Current biology : CB. 25(11):1526-34
Satija, R., Farrell, J.A., Gennert, D., Schier, A.F., Regev, A. (2015) Spatial reconstruction of single-cell gene expression data. Nat. Biotechnol.. 33(5):495-502
Dubrulle, J., Jordan, B.M., Akhmetova, L., Farrell, J.A., Kim, S.H., Solnica-Krezel, L., Schier, A.F. (2015) Response to Nodal morphogen gradient is determined by the kinetics of target gene induction. eLIFE. 4
Liu, J., Merkle, F.T., Gandhi, A.V., Gagnon, J.A., Woods, I.G., Chiu, C.N., Shimogori, T., Schier, A.F., Prober, D.A. (2015) Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9. Development (Cambridge, England). 142(6):1113-24
Haesemeyer, M., Schier, A.F. (2015) The study of psychiatric disease genes and drugs in zebrafish. Current opinion in neurobiology. 30C:122-130
Pauli, A., Valen, E., Schier, A.F. (2015) Identifying (non-)coding RNAs and small peptides: Challenges and opportunities. BioEssays : news and reviews in molecular, cellular and developmental biology. 37(1):103-12
Rabani, M., Raychowdhury, R., Jovanovic, M., Rooney, M., Stumpo, D.J., Pauli, A., Hacohen, N., Schier, A.F., Blackshear, P.J., Friedman, N., Amit, I., Regev, A. (2014) High-Resolution Sequencing and Modeling Identifies Distinct Dynamic RNA Regulatory Strategies. Cell. 159(7):1698-710
Gagnon, J.A., Valen, E., Thyme, S.B., Huang, P., Ahkmetova, L., Pauli, A., Montague, T.G., Zimmerman, S., Richter, C., Schier, A.F. (2014) Efficient Mutagenesis by Cas9 Protein-Mediated Oligonucleotide Insertion and Large-Scale Assessment of Single-Guide RNAs. PLoS One. 9:e98186
Woods, I.G., Schoppik, D., Shi, V.J., Zimmerman, S., Coleman, H.A., Greenwood, J., Soucy, E.R., Schier, A.F. (2014) Neuropeptidergic signaling partitions arousal behaviors in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34:3142-60
Pauli, A., Norris, M.L., Valen, E., Chew, G.L., Gagnon, J.A., Zimmerman, S., Mitchell, A., Ma, J., Dubrulle, J., Reyon, D., Tsai, S.Q., Joung, J.K., Saghatelian, A., and Schier, A.F. (2014) Toddler: an embryonic signal that promotes cell movement via Apelin receptors. Science (New York, N.Y.). 343(6172):1248636
Zhang, Y., Vastenhouw, N.L., Feng, J., Fu, K., Wang, C., Ge, Y., Pauli, A., van Hummelen, P., Schier, A.F., and Liu, X.S. (2014) Canonical nucleosome organization at promoters forms during genome activation. Genome research. 24(2):260-6
Rihel, J., and Schier, A.F. (2013) Sites of action of sleep and wake drugs: insights from model organisms. Current opinion in neurobiology. 23(5):831-40
Pan, Y.A., Freundlich, T., Weissman, T.A., Schoppik, D., Wang, X.C., Zimmerman, S., Ciruna, B., Sanes, J.R., Lichtman, J.W., and Schier, A.F. (2013) Zebrabow: multispectral cell labeling for cell tracing and lineage analysis in zebrafish. Development (Cambridge, England). 140(13):2835
Chew, G.L., Pauli, A., Rinn, J.L., Regev, A., Schier, A.F., and Valen, E. (2013) Ribosome profiling reveals resemblance between long non-coding RNAs and 5' leaders of coding RNAs. Development (Cambridge, England). 140(13):2828-2834
Xiong, F., Tentner, A.R., Huang, P., Gelas, A., Mosaliganti, K.R., Souhait, L., Rannou, N., Swinburne, I.A., Obholzer, N.D., Cowgill, P.D., Schier, A.F., and Megason, S.G. (2013) Specified neural progenitors sort to form sharp domains after noisy shh signaling. Cell. 153(3):550-561
Schier, A.F. (2013) Genomics: Zebrafish earns its stripes. Nature. 496:443-444
Levitz, J., Pantoja, C., Gaub, B., Janovjak, H., Reiner, A., Hoagland, A., Schoppik, D., Kane, B., Stawski, P., Schier, A.F., Trauner, D., and Isacoff, E.Y. (2013) Optical control of metabotropic glutamate receptors. Nature Neuroscience. 16(4):507-16
Bianco, I.H., Ma, L.H., Schoppik, D., Robson, D.N., Orger, M.B., Beck, J.C., Li, J.M., Schier, A.F., Engert, F., and Baker, R. (2012) The Tangential Nucleus Controls a Gravito-inertial Vestibulo-ocular Reflex. Current biology : CB. 22(14):1285-1295
Low, S.E., Woods, I.G., Lachance, M., Ryan, J., Schier, A.F., and Saint-Amant, L. (2012) Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b. Journal of neurophysiology. 108(1):148-159
Vastenhouw, N.L., and Schier, A.F. (2012) Bivalent histone modifications in early embryogenesis. Current opinion in cell biology. 24(3):374-386
Panizzi, J.R., Becker-Heck, A., Castleman, V.H., Al-Mutairi, D.A., Liu, Y., Loges, N.T., Pathak, N., Austin-Tse, C., Sheridan, E., Schmidts, M., Olbrich, H., Werner, C., Häffner, K., Hellman, N., Chodhari, R., Gupta, A., Kramer-Zucker, A., Olale, F., Burdine, R.D., Schier, A.F., O'Callaghan, C., Chung, E.M., Reinhardt, R., Mitchison, H.M., King, S.M., Omran, H., and Drummond, I.A. (2012) CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms. Nature Genetics. 44(6):714-719
Müller, P., Rogers, K.W., Jordan, B.M., Lee, J.S., Robson, D., Ramanathan, S., Schier, A.F. (2012) Differential Diffusivity of Nodal and Lefty Underlies a Reaction-Diffusion Patterning System. Science (New York, N.Y.). 336(6082):721-724
Ahrens, M.B., Li, J.M., Orger, M.B., Robson, D.N., Schier, A.F., Engert, F., and Portugues, R. (2012) Brain-wide neuronal dynamics during motor adaptation in zebrafish. Nature. 485(7399):471-477
Stooke-Vaughan, G.A., Huang, P., Hammond, K.L., Schier, A.F., and Whitfield, T.T. (2012) The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle. Development (Cambridge, England). 139(10):1777-1787
Xu, C., Fan, Z.P., Müller, P., Fogley, R., Dibiase, A., Trompouki, E., Unternaehrer, J., Xiong, F., Torregroza, I., Evans, T., Megason, S.G., Daley, G.Q., Schier, A.F., Young, R.A., and Zon, L.I. (2012) Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway. Developmental Cell. 22(3):625-238
Pauli, A., Valen, E., Lin, M.F., Garber, M., Vastenhouw, N.L., Levin, J.Z., Fan, L., Sandelin, A., Rinn, J.L., Regev, A., and Schier, A.F. (2012) Systematic identification of long non-coding RNAs expressed during zebrafish embryogenesis. Genome research. 22(3):577-591
Rihel, J., and Schier, A.F. (2012) Behavioral screening for neuroactive drugs in zebrafish. Developmental Neurobiology. 72(3):373-385
Pan, Y.A., Choy, M., Prober, D.A., and Schier, A.F. (2012) Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons. Development (Cambridge, England). 139(3):591-600
Huang, P., Xiong, F., Megason, S.G., and Schier, A.F. (2012) Attenuation of notch and hedgehog signaling is required for fate specification in the spinal cord. PLoS Genetics. 8(6):e1002762
Pan, Y.A., Caron, S.J., and Schier, A.F. (2012) BAPTI and BAPTISM Birthdating of Neurons in Zebrafish. Cold Spring Harbor protocols. 2012(1):pdb.prot067520
Pan, Y.A., Livet, J., Sanes, J.R., Lichtman, J.W., and Schier, A.F. (2011) Multicolor brainbow imaging in zebrafish. Cold Spring Harbor protocols. 2011:pdb.prot5546
Vastenhouw, N.L., Zhang, Y., Woods, I.G., Imam, F., Regev, A., Liu, X.S., Rinn, J., and Schier, A.F. (2010) Chromatin signature of embryonic pluripotency is established during genome activation. Nature. 464(7290):922-926
Harvey, S.A., Tümpel, S., Dubrulle, J., Schier, A.F., and Smith, J.C. (2010) no tail integrates two modes of mesoderm induction. Development (Cambridge, England). 137(7):1127-1135
Naumann, E.A., Kampff, A.R., Prober, D.A., Schier, A.F., and Engert, F. (2010) Monitoring neural activity with bioluminescence during natural behavior. Nature Neuroscience. 13(4):513-520
Rihel, J., Prober, D.A., Arvanites, A., Lam, K., Zimmerman, S., Jang, S., Haggarty, S.J., Kokel, D., Rubin, L.L., Peterson, R.T., and Schier, A.F. (2010) Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation. Science (New York, N.Y.). 327(5963):348-351
Rihel, J., Prober, D.A., and Schier, A.F. (2010) Chapter 11 - Monitoring sleep and arousal in zebrafish. Meth. Cell. Biol.. 100:281-294
Huang, P., and Schier, A.F. (2009) Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia. Development (Cambridge, England). 136(18):3089-3098
de Campos-Baptista, M.I., Holtzman, N.G., Yelon, D., and Schier, A.F. (2008) Nodal signaling promotes the speed and directional movement of cardiomyocytes in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists. 237(12):3624-3633
Caron, S.J., Prober, D., Choy, M., and Schier, A.F. (2008) In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis. Development (Cambridge, England). 135(19):3259-3269
Prober, D.A., Zimmerman, S., Myers, B.R., McDermott, B.M. Jr, Kim, S.H., Caron, S., Rihel, J., Solnica-Krezel, L., Julius, D., Hudspeth, A.J., and Schier, A.F. (2008) Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28(40):10102-10110
Douglass, A.D., Kraves, S., Deisseroth, K., Schier, A.F., and Engert, F. (2008) Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons. Current biology : CB. 18(15):1133-1137
Woods, I.G., and Schier, A.F. (2008) Targeted mutagenesis in zebrafish. Nat. Biotechnol.. 26(6):650-651
Knaut, H., and Schier, A.F. (2008) Clearing the path for germ cells. Cell. 132(3):337-339
Choi, P.S., Zakhary, L., Choi, W.Y., Caron, S., Alvarez-Saavedra, E., Miska, E.A., McManus, M., Harfe, B., Giraldez, A.J., Horvitz, R.H., Schier, A.F., and Dulac, C. (2008) Members of the miRNA-200 Family Regulate Olfactory Neurogenesis. Neuron. 57(1):41-55
Bennett, J.T., Stickney, H.L., Choi, W.Y., Ciruna, B., Talbot, W.S., and Schier, A.F. (2007) Maternal nodal and zebrafish embryogenesis. Nature. 450(7167):E1-E4
Choi, W.Y., Giraldez, A.J., and Schier, A.F. (2007) Target Protectors Reveal Dampening and Balancing of Nodal Agonist and Antagonist by miR-430. Science (New York, N.Y.). 318(5848):271-274
Bennett, J.T., Joubin, K., Cheng, S., Aanstad, P., Herwig, R., Clark, M., Lehrach, H., and Schier, A.F. (2007) Nodal signaling activates differentiation genes during zebrafish gastrulation. Developmental Biology. 304(2):525-540
Prober, D.A., Rihel, J., Onah, A.A., Sung, R.J., and Schier, A.F. (2006) Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(51):13400-13410
Mishima, Y., Giraldez, A.J., Takeda, Y., Fujiwara, T., Sakamoto, H., Schier, A.F., and Inoue, K. (2006) Differential Regulation of Germline mRNAs in Soma and Germ Cells by Zebrafish miR-430. Current biology : CB. 16(21):2135-2142
Obara, T., Mangos, S., Liu, Y., Zhao, J., Wiessner, S., Kramer-Zucker, A.G., Olale, F., Schier, A.F., and Drummond, I.A. (2006) Polycystin-2 Immunolocalization and Function in Zebrafish. Journal of the American Society of Nephrology : JASN. 17(10):2706-2718
Giraldez, A.J., Mishima, Y., Rihel, J., Grocock, R.J., Van Dongen, S., Inoue, K., Enright, A.J., and Schier, A.F. (2006) Zebrafish MiR-430 Promotes Deadenylation and Clearance of Maternal mRNAs. Science (New York, N.Y.). 312(5770):75-79
Ciruna, B., Jenny, A., Lee, D., Mlodzik, M., and Schier, A.F. (2006) Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature. 439(7073):220-224
Schier, A.F., and Giraldez, A.J. (2006) MicroRNA function and mechanism: insights from zebra fish. Cold Spring Harbor symposia on quantitative biology. 71:195-203
Schier, A.F. (2005) Axis formation: squint comes into focus. Current biology : CB. 15(24):1002-1005
Knaut, H., Blader, P., Strähle, U., and Schier, A.F. (2005) Assembly of trigeminal sensory Ganglia by chemokine signaling. Neuron. 47(5):653-666
Sagasti, A., Guido, M.R., Raible, D.W., and Schier, A.F. (2005) Repulsive interactions shape the morphologies and functional arrangement of zebrafish peripheral sensory arbors. Current biology : CB. 15(9):804-814
Giraldez, A.J., Cinalli, R.M., Glasner, M.E., Enright, A.J., Thomson, M.J., Baskerville, S., Hammond, S.M., Bartel, D.P., and Schier, A.F. (2005) MicroRNAs Regulate Brain Morphogenesis in Zebrafish. Science (New York, N.Y.). 308(5723):833-838
Kramer-Zucker, A.G., Olale, F., Haycraft, C.J., Yoder, B.K., Schier, A.F., and Drummond, I.A. (2005) Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis. Development (Cambridge, England). 132(8):1907-1921
Dutta, S., Dietrich, J.E., Aspock, G., Burdine, R.D., Schier, A., Westerfield, M., and Varga, Z.M. (2005) pitx3 defines an equivalence domain for lens and anterior pituitary placode. Development (Cambridge, England). 132(7):1579-1590
Tyurina, O.V., Guner, B., Popova, E., Feng, J., Schier, A.F., Kohtz, J.D., and Karlstrom, R.O. (2005) Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling. Developmental Biology. 277(2):537-556
Le Good, J.A., Joubin, K., Giraldez, A.J., Ben-Haim, N., Beck, S., Chen, Y., Schier, A.F., and Constam, D.B. (2005) Nodal stability determines signaling range. Current biology : CB. 15(1):31-36
Schier, A.F., and Talbot, W.S. (2005) Molecular Genetics of Axis Formation in Zebrafish. Annual review of genetics. 39:561-613
Nakano, Y., Kim, H.R., Kawakami, A., Roy, S., Schier, A.F., and Ingham, P.W. (2004) Inactivation of dispatched 1 by the chameleon mutation disrupts Hedgehog signalling in the zebrafish embryo. Developmental Biology. 269(2):381-392
Kunwar, P.S., Zimmerman, S., Bennett, J.T., Chen, Y., Whitman, M., and Schier, A.F. (2003) Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction. Development (Cambridge, England). 130(23):5589-5599
Dougan, S.T., Warga, R.M., Kane, D.A., Schier, A.F., and Talbot, W.S. (2003) The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm. Development (Cambridge, England). 130(9):1837-1851
Karlstrom, R.O., Tyurina, O.V., Kawakami, A., Nishioka, N., Talbot, W.S., Sasaki, H., and Schier, A.F. (2003) Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development (Cambridge, England). 130(8):1549-1564
Schier, A.F. (2003) Chemokine signaling: rules of attraction. Current biology : CB. 13(5):R192-194
Cheng, S.K., Olale, F., Bennett, J.T., Brivanlou, A.H., and Schier, A.F. (2003) EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1. Genes and Development. 17(1):31-36
Chen, Y. and Schier, A.F. (2002) Lefty proteins are long-range inhibitors of squint-mediated nodal signaling. Current biology : CB. 12(24):2124-2128
Ciruna, B., Weidinger, G., Knaut, H., Thisse, B., Thisse, C., Raz, E., and Schier, A.F. (2002) Production of maternal-zygotic mutant zebrafish by germ-line replacement. Proc. Natl. Acad. Sci. USA. 99(23):14919-14924
Moon, H.S., Jacobson, E.M., Khersonsky, S.M., Luzung, M.R., Walsh, D.P., Xiong, W.N., Lee, J.W., Parikh, P.B., Lam, J.C., Kang, T.W., Rosania, G.R., Schier, A.F., and Chang, Y.T. (2002) A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening. Journal of the American Chemical Society. 124(39):11608-11609
de la Cruz, J.M., Bamford, R.N., Burdine, R.D., Roessler, E., Barkovich, A.J., Donnai, D., Schier, A.F., and Muenke, M. (2002) A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects. Human genetics. 110(5):422-428
Yamashita, S., Miyagi, C., Carmany-Rampey, A., Shimizu, T., Fujii, R., Schier, A.F., and Hirano, T. (2002) Stat3 controls cell movements during zebrafish gastrulation. Developmental Cell. 2(3):363-375
Kimelman, D. and Schier, A.F. (2002) Mesoderm induction and patterning. Results Probl. Cell Diff.. 40:15-27
Carmany-Rampey, A. and Schier, A.F. (2001) Single-cell internalization during zebrafish gastrulation. Current biology : CB. 11(16):1261-1265
Schier, A.F. (2001) Axis formation and patterning in zebrafish. Current opinion in genetics & development. 11(4):393-404
Imai, Y., Gates, M.A., Melby, A.E., Kimelman, D., Schier, A.F., and Talbot, W.S (2001) The homeobox genes vox and vent are redundant repressors of dorsal fates in zebrafish. Development (Cambridge, England). 128(12):2407-2420
Chen, Y. and Schier, A.F. (2001) The zebrafish Nodal signal Squint functions as a morphogen. Nature. 411(6837):607-610
Schier, A.F. and Talbot, W.S. (2001) Nodal signaling and the zebrafish organizer. The International journal of developmental biology. 45(1):289-97
Bamford, R.N., Roessler, E., Burdine, R.D., Saplakoglu, U., de la Cruz, J., Splitt, M., Towbin, J., Bowers, P., Marino, B., Schier, A.F., Shen, M.M., Muenke, M., and Casey, B. (2000) Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects. Nature Genetics. 26(3):365-369
Concha, M.L., Burdine, R.D., Russell, C., Schier, A.F., and Wilson, S.W. (2000) A nodal signaling pathway regulates the laterality of neuroanatomical asymmetries in the zebrafish forebrain. Neuron. 28(2):399-409
Sirotkin, H.I., Gates, M.A., Kelly, P.D., Schier, A.F., and Talbot, W.S. (2000) fast1 is required for the development of dorsal axial structures in zebrafish. Current biology : CB. 10(17):1051-1054
Shen, M.M. and Schier, A.F. (2000) The EGF-CFC gene family in vertebrate development. Trends in genetics : TIG. 16(7):303-309
Sirotkin, H.I., Dougan, S.T., Schier, A.F., and Talbot, W.S. (2000) bozozok and squint act in parallel to specify dorsal mesoderm and anterior neuroectoderm in zebrafish. Development (Cambridge, England). 127(12):2583-92
Feldman, B., Dougan, S.T., Schier, A.F., and Talbot, W.S. (2000) Nodal-related signals establish mesendodermal fate and trunk neural identity in zebrafish. Current biology : CB. 10(9):531-534
Imai, Y., Feldman, B., Schier, A.F., and Talbot, W.S. (2000) Analysis of chromosomal rearrangements induced by postmeiotic mutagenesis with ethylnitrosourea in zebrafish. Genetics. 155(1):261-272
Burdine, R.D. and Schier, A.F. (2000) Conserved and divergent mechanisms in left-right axis formation. Genes and Development. 14(7):763-776
Kelly, P.D., Chu, F., Woods, I.G., Ngo-Hazelett, P., Cardozo, T., Huang, H., Kimm, F., Liao, L., Yan, Y.L., Zhou, Y., Johnson, S.L., Abagyan, R., Schier, A.F., Postlethwait, J.H., and Talbot, W.S. (2000) Genetic linkage mapping of zebrafish genes and ESTs. Genome research. 10(4):558-567
Gritsman, K., Talbot, W.S., and Schier, A.F. (2000) Nodal signaling patterns the organizer. Development (Cambridge, England). 127(5):921-932
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