ZFIN Person: Copeland, Paul

ZFIN ID: ZDB-PERS-231218-4

ZFIN ID: ZDB-PERS-231218-4

Copeland, Paul

Email:	paul.copeland@rutgers.edu
URL:	https://sites.rutgers.edu/copeland-lab/
Affiliation:	Copeland Lab
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ORCID ID:	0000000333430587

BIOGRAPHY AND RESEARCH INTERESTS

The Copeland Lab has been at Rutgers Robert Wood Johnson Medical School since 2002. We study the essential trace element selenium with an emphasis on the molecular requirements for the incorporation of selenocysteine. About 8 years ago we turned to zebrafish to build a tractable in vivo model system in which we could ask mechanistic questions.

PUBLICATIONS

Kiledjian, N.T., Shah, R., Vetick, M.B., Copeland, P.R. (2022) The expression of essential selenoproteins during development requires SECIS-binding protein 2-like. Life science alliance. 5(5):

Copeland, P., Vetick, M. (2019) A Zebrafish Model for Selenoprotein Synthesis and Function (OR11-01-19). Current developments in nutrition. 3(Suppl 1)

Shetty, S.P., Copeland, P.R. (2018) The Selenium Transport Protein, Selenoprotein P, Requires Coding Sequence Determinants to Promote Efficient Selenocysteine Incorporation. Journal of molecular biology. 430:5217-5232

Shetty, S.P., Sturts, R.J., Vetick, M.B., Copeland, P.R. (2018) Processive incorporation of multiple selenocysteine residues is driven by a novel feature of the selenocysteine insertion sequence. The Journal of biological chemistry. 293(50):19377-19386

Shetty, S., Marsicano, J.R., Copeland, P.R. (2017) Uptake and Utilization of Selenium from Selenoprotein P. Biological trace element research. 181(1):54-61

Tujebajeva, R.M., Copeland, P.R., Xu, X.M., Carlson, B.A., Harney, J.W., Driscoll, D.M., Hatfield, D.L., and Berry, M.J. (2000) Decoding apparatus for eukaryotic selenocysteine insertion. EMBO reports. 1(2):158-163

NON-ZEBRAFISH PUBLICATIONS