ZFIN ID: ZDB-PERS-220929-1
Li, Xi
Email: xili_ihb@126.com
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Affiliation: Xi Li Lab
Address: The Affiliated Kangning Hospital of Wenzhou Medical University, No. 1 Shengjin Road, Lucheng District, Wenzhou City, Zhejiang Province, China.
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BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Luo, Y., Zheng, M., Su, Z., Cai, C., Li, X. (2023) Transcriptome profile of reserpine-induced locomotor behavioral changes in zebrafish (Danio rerio). Progress in neuro-psychopharmacology & biological psychiatry. 129:110874
Wang, C., Li, M., Gui, W., Shi, H., Wang, P., Chen, J., Fent, K., Zhang, K., Dai, J., Li, X., Zhao, Y. (2023) Prednisolone Accelerates Embryonic Development of Zebrafish via Glucocorticoid Receptor Signaling at Low Concentrations. Environmental science & technology. 57(42):15794-15805
Huang, Z., Luo, Y., Chen, C., Zhou, C., Su, Z., Cai, C., Li, X., Wu, W. (2023) miR-325-3p Reduces Proliferation and Promotes Apoptosis of Gastric Cancer Cells by Inhibiting Human Antigen R. Canadian journal of gastroenterology & hepatology. 2023:68828516882851
Su, Z., Dai, Z., Qin, F., Zhang, H., Zheng, M., Zhu, Y., Tong, Z., Weihong, S., Li, X. (2023) Valbenazine promotes body growth via growth hormone signaling during zebrafish embryonic development. Toxicology and applied pharmacology. 477:116674
Deng, S., Guo, A., Huang, Z., Guan, K., Zhu, Y., Chan, C., Gui, J., Song, C., Li, X. (2023) The exploration of neuroinflammatory mechanism by which CRHR2 deficiency induced anxiety disorder. Progress in neuro-psychopharmacology & biological psychiatry. 128:110844
Zhou, C., Luo, Y., Huang, Z., Dong, F., Lin, J., Luo, L., Li, X., Cai, C., Wu, W. (2023) ELAVL1 promotes LPS-induced endothelial cells injury through modulation of cytokine storm. Immunobiology. 228:152412152412
Guan, K., Shan, C., Guo, A., Gao, X., Li, X. (2023) Ghrelin regulates hyperactivity-like behaviors via growth hormone signaling pathway in zebrafish (Danio rerio). Frontiers in endocrinology. 14:11632631163263
Su, Z., Guan, K., Liu, Y., Zhang, H., Huang, Z., Zheng, M., Zhu, Y., Zhang, H., Song, W., Li, X. (2022) Developmental and behavioral toxicity assessment of opicapone in zebrafish embryos. Ecotoxicology and environmental safety. 249:114340114340
Shi, S., Shu, T., Li, X., Lou, Q., Jin, X., He, J., Yin, Z., Zhai, G. (2022) Characterization of the Interrenal Gland and Sexual Traits Development in cyp17a2-Deficient Zebrafish. Frontiers in endocrinology. 13:910639
Zhu, Y., Yang, D., Duan, X., Zhang, Y., Chen, D., Gong, Z., Liu, C. (2021) Perfluorooctane Sulfonate Promotes Doxycycline-induced Liver Tumor Progression in Male Krasv12 Transgenic Zebrafish. Environmental research. 196:110962
Niu, X., Xu, S., Yang, Q., Xu, X., Zheng, M., Li, X., Guan, W. (2021) Toxic effects of the dinoflagellate Karenia mikimotoi on zebrafish (Danio rerio) larval behavior. Harmful algae. 103:101996
Shi, X., Guan, K., Peng, X., Xu, B., Zhou, X., Wang, S., Xu, S., Zheng, M., Huang, J., Wan, X., Guan, W., Su, K.P., Ye, M., Gao, X., Yin, Z., Li, X. (2021) Ghrelin Modulates Dopaminergic Neuron Formation and Attention Deficit Hyperactivity Disorder-like Behaviors: From Animals to Human Models. Brain, behavior, and immunity. 94:327-337
Wei, H., Wang, S., Xu, E.G., Liu, J., Li, X., Wang, Z. (2019) Synergistic toxicity of microcystin-LR and Cu to zebrafish (Danio rerio). The Science of the total environment. 713:136393
Wang, S., Duan, M., Guan, K., Zhou, X., Zheng, M., Shi, X., Ye, M., Guan, W., Kuver, A., Huang, M., Liu, Y., Dai, K., Li, X. (2019) Developmental neurotoxicity of reserpine exposure in zebrafish larvae (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 223:115-123
Wang, X., Feng, X., Zhuang, Y., Lu, J., Wang, Y., Gonçalves, R.J., Li, X., Lou, Y., Guan, W. (2019) Effects of ocean acidification and solar ultraviolet radiation on physiology and toxicity of dinoflagellate Karenia mikimotoi. Harmful algae. 81:1-9
Zhou, X., Wang, S., Zheng, M., Kuver, A., Wan, X., Dai, K., Li, X. (2018) Phosphorylation of ELAVL1 (Ser219/Ser316) mediated by PKC is required for erythropoiesis. Biochimica et biophysica acta. Molecular cell research. 1866(2):214-224
Guan, W., Si, R., Li, X., Cai, J., Chen, S. (2018) Interactive effect of nitrogen source and high CO2 concentration on the growth of the dinoflagellate Alexandrium tamarense and its toxicity to zebrafish (Danio rerio) embryos.. Marine pollution bulletin. 133:626-635
Li, X., Lu, Y.C., Dai, K., Torregroza, I., Hla, T., Evans, T. (2014) Elavl1a regulates zebrafish erythropoiesis via posttranscriptional control of gata1. Blood. 123:1384-92
Chang, S.H., Lu, Y.C., Li, X., Hsieh, W.Y., Xiong, Y., Ghosh, M., Evans, T., Elemento, O., and Hla, T. (2013) Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of VEGF-A expression and angiogenesis. The Journal of biological chemistry. 288(7):4908-4921
Li, X., Nie, F., Yin, Z., and He, J. (2011) Enhanced hyperplasia in muscles of transgenic zebrafish expressing Follistatin1. Science China. Life sciences. 54(2):159-165
Li, X., He, J., Hu, W., and Yin, Z. (2009) The essential role of endogenous ghrelin in growth hormone expression during zebrafish adenohypophysis development. Endocrinology. 150(6):2767-2774

NON-ZEBRAFISH PUBLICATIONS
Wang, D., Yin, Y., Wang, S., Zhao, T., Gong, F., Zhao, Y., Wang, B., Huang, Y., Cheng, Z., Zhu, G., Wang, Z., Wang, Y., Ren, J., Liang, G., Li, X., Huang, Z. FGF1ΔHBS prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression. Signal Transduction and Targeted Therapy. 2021, 6, 133.

Shi, X., Wang, W., Li, J., Wang, T., Lin, Y., Huang, S., Kuver, A., Chen, C., Hla, T., Li, X., Dai, K. Sphingosine 1-phosphate receptor 1 regulates cell-surface localization of membrane proteins in endothelial cells. Biochimica et Biophysica Acta (BBA) - General Subjects. 2019, 1863, 1079-1087.

Wang, S., Zhou, H., Wu, D., Ni, H., Chen, Z., Chen, C., Xiang, Y., Dai, K., Chen, X., Li, X. MicroRNA let-7a regulates angiogenesis by targeting TGFBR3 mRNA. Journal of Cellular and Molecular Medicine. 2019, 23, 556-567.
Lu, Y., Chang, S., Hafner, M., Li, X., Tuschl, T., Elemento, O., Hla, T. ELAVL1 Modulates Transcriptome-wide miRNA Binding in Murine Macrophages. Cell Reports. 2014, 9, 2330-2343.
Pi, X., Xie, L., Portbury, A. L., Kumar, S., Lockyer, P., Li, X., Patterson, C. NADPH Oxidase–Generated Reactive Oxygen Species Are Required for Stromal Cell–Derived Factor-1α–Stimulated Angiogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. 2014, 34, 2023-2032.