ZFIN Person: Coffman, James A.

ZFIN ID: ZDB-PERS-210219-5

ZFIN ID: ZDB-PERS-210219-5

Coffman, James A.

Email:	jcoffman@mdibl.org
URL:	http://mdibl.org/faculty/james-a-coffman/
Affiliation:	Coffman Lab
Address:	MDI Biological Laboratory P.O. Box 35, Salisbury Cove, ME 04672
Country:	United States
Phone:	207-288-9880, Ext. 444
Fax:
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

The Coffman laboratory examines the role of glucocorticoid signaling and the glucocorticoid-responsive gene regulatory network in stress-induced developmental programming in vertebrates, using zebrafish as a research model.

PUBLICATIONS

Drepanos, L., Gans, I.M., Grendler, J., Guitar, S., Fuqua, J.H., Maki, N.J., Tilden, A.R., Graber, J.H., Coffman, J.A. (2023) Loss of Krüppel-like factor 9 deregulates both physiological gene expression and development. Scientific Reports. 13:1223912239

Gans, I.M., Grendler, J., Babich, R., Jayasundara, N., Coffman, J.A. (2021) Glucocorticoid-Responsive Transcription Factor Krüppel-Like Factor 9 Regulates fkbp5 and Metabolism. Frontiers in cell and developmental biology. 9:727037

Hartig, E.I., Zhu, S., King, B.L., Coffman, J.A. (2020) Chronic cortisol exposure in early development leads to neuroendocrine dysregulation in adulthood. BMC research notes. 13:366

Gans, I., Hartig, E.I., Zhu, S., Tilden, A.R., Hutchins, L.N., Maki, N.J., Graber, J.H., Coffman, J.A. (2020) Klf9 is a key feedforward regulator of the transcriptomic response to glucocorticoid receptor activity. Scientific Reports. 10:11415

Hartig, E.I., Zhu, S., King, B.L., Coffman, J.A. (2016) Cortisol-treated zebrafish embryos develop into pro-inflammatory adults with aberrant immune gene regulation. Biology Open. 5(8):1134-41

NON-ZEBRAFISH PUBLICATIONS