ZFIN ID: ZDB-PERS-201119-2
Luo, Kathy Qian
Email: kluo@um.edu.mo
URL: http://fhs.um.edu.mo/en/staff/kathy-luo/
Affiliation: Kathy Qian Luo Lab
Address: 4038, N22, University of Macau, Taipa, Macao SAR
Country: China
Phone: +853-88224233
Fax:
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS
BIOGRAPHY

Prof. Kathy Qian Luo received her BS and MS degrees from Peking University and Ph.D. degree from the University of British Columbia in Canada. She worked as a Postdoctoral Fellow at California Institute of Technology in USA, as a Visiting Assistant Professor at the Hong Kong University of Science and Technology, and as an Associate Professor at Nanyang Technological University in Singapore. Prof. Luo is now a Full Professor in the Faculty of Health Sciences at the University of Macau. Her research areas include cancer biology, anti-cancer drug discovery and aging research. Prof. Luo has published 77 top quality international journal articles with total citations of 4,841 and h-index of 35. She has obtained 7 patents from USA, China and Singapore, also obtained 25 research grants with a total funding of over 10 million US dollars.

STATEMENT OF RESEARCH INTERESTS

Our research interests include: (1) Identify driver genes that can increase cancer cells survival in circulation, metastasis and tumor growth using zebrafish and mice as model animals. (2) Discover new agents against metastatic and drug resistant cancer cells. (3) Generate transgenic zebrafish for aging research and toxicity study.


PUBLICATIONS
Tao, J., Wei, Z., Cheng, Y., Xu, M., Li, Q., Lee, S.M., Ge, W., Luo, K.Q., Wang, X., Zheng, Y. (2022) Apoptosis-Sensing Xenograft Zebrafish Tumor Model for Anticancer Evaluation of Redox-Responsive Cross-Linked Pluronic Micelles. ACS applied materials & interfaces. 14(35):39775-39786
Yang, H., Jia, H., Zhao, Q., Luo, K.Q. (2022) Visualization of natural killer cell-mediated killing of cancer cells at single-cell resolution in live zebrafish. Biosensors & bioelectronics. 216:114616
Jia, H., Luo, K.Q. (2020) Fluorescence resonance energy transfer-based sensor zebrafish for detecting toxic agents with single-cell sensitivity. Journal of hazardous materials. 408:124826
Jia, H., Song, Y., Huang, B., Ge, W., Luo, K.Q. (2020) Engineered Sensor Zebrafish for Fast Detection and Real-Time Tracking of Apoptosis at Single-Cell Resolution in Live Animals. ACS sensors. 5(3):823-830
Wang, Q., Luo, M., Wei, N., Chang, A., Luo, K.Q. (2019) Development of a Liposomal Formulation of Acetyltanshinone IIA for Breast Cancer Therapy. Molecular pharmaceutics. 16(9):3873-3886
Ma, S., Fu, A., Chiew, G.G., Luo, K.Q. (2017) Hemodynamic shear stress stimulates migration and extravasation of tumor cells by elevating cellular oxidative level. Cancer letters. 388:239-248
Wang, Q., Wei, N., Liu, X., Chang, A., Qian Luo, K. (2017) Enhancement of the bioavailability of a novel anticancer compound (acetyltanshinone IIA) by encapsulation within mPEG-PLGA nanoparticles: a study of formulation optimization, toxicity, and pharmacokinetics. Oncotarget. 8(7):12013-12030
Fu, A., Ma, S., Wei, N., Tan, B.X., Tan, E.Y., Luo, K.Q. (2016) High expression of MnSOD promotes survival of circulating breast cancer cells and increases their resistance to doxorubicin. Oncotarget. 7(31):50239-50257

NON-ZEBRAFISH PUBLICATIONS
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