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Research
General Information
ZIRC
ZFIN ID: ZDB-PERS-151014-1
Liu, Mugen
Email: lium@hust.edu.cn
URL:
Affiliation: Mugen Liu Lab
Address:
Country: China
Phone:
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Orcid ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Ping, J., Zhao, F., Nie, J., Yu, T., Zhu, D., Liu, M., Fei, P. (2019) Propagating-path uniformly scanned light sheet excitation microscopy for isotropic volumetric imaging of large specimens. Journal of Biomedical Optics. 24:1-5
Qu, Z., Yimer, T.A., Xie, S., Wong, F., Yu, S., Liu, X., Han, S., Ma, J., Lu, Z., Hu, X., Qin, Y., Huang, Y., Lv, Y., Li, J., Tang, Z., Liu, F., Liu, M. (2019) Knocking out lca5 in zebrafish causes cone-rod dystrophy due to impaired outer segment protein trafficking. Biochimica et biophysica acta. Molecular basis of disease. 1865(10):2694-2705
Xie, S., Han, S., Qu, Z., Liu, F., Li, J., Yu, S., Reilly, J., Tu, J., Liu, X., Lu, Z., Hu, X., Yimer, T.A., Qin, Y., Huang, Y., Lv, Y., Jiang, T., Shu, X., Tang, Z., Jia, H., Wong, F., Liu, M. (2019) Knockout of Nr2e3 prevents rod photoreceptor differentiation and leads to selective L-/M-cone photoreceptor degeneration in zebrafish. Biochimica et biophysica acta. Molecular basis of disease. 1865(6):1273-1283
Yu, S., Jiang, T., Jia, D., Han, Y., Liu, F., Huang, Y., Qu, Z., Zhao, Y., Tu, J., Lv, Y., Li, J., Hu, X., Lu, Z., Han, S., Qin, Y., Liu, X., Xie, S., Wang, Q.K., Tang, Z., Luo, D., Liu, M. (2018) BCAS2 is essential for hematopoietic stem and progenitor cell maintenance during zebrafish embryogenesis. Blood. 133(8):805-815
Han, S., Liu, X., Xie, S., Gao, M., Liu, F., Yu, S., Sun, P., Wang, C., Archacki, S., Lu, Z., Hu, X., Qin, Y., Qu, Z., Huang, Y., Lv, Y., Tu, J., Li, J., Yimer, T.A., Jiang, T., Tang, Z., Luo, D., Chen, F., Liu, M. (2018) Knockout of ush2a gene in zebrafish causes hearing impairment and late onset rod-cone dystrophy. Human genetics. 137(10):779-794
Raghupathy, R.K., Zhang, X., Liu, F., Alhasani, R.H., Biswas, L., Akhtar, S., Pan, L., Moens, C.B., Li, W., Liu, M., Kennedy, B.N., Shu, X. (2017) Rpgrip1 is required for rod outer segment development and ciliary protein trafficking in zebrafish. Scientific Reports. 7:16881
Gao, M., Huang, Y., Wang, L., Huang, M., Liu, F., Liao, S., Yu, S., Lu, Z., Han, S., Hu, X., Qu, Z., Liu, X., Assefa Yimer, T., Yang, L., Tang, Z., Li, D.W., Liu, M. (2017) HSF4 regulates lens fiber cell differentiation by activating p53 and its downstream regulators. Cell Death & Disease. 8:e3082
Yu, S., Li, C., Biswas, L., Hu, X., Liu, F., Reilly, J., Liu, X., Liu, Y., Huang, Y., Lu, Z., Han, S., Wang, L., Liu, J.Y., Jiang, T., Shu, X., Wong, F., Tang, Z., Liu, M. (2017) CERKL gene knockout disturbs photoreceptor outer segment phagocytosis and causes rod-cone dystrophy in zebrafish. Human molecular genetics. 26(12):2335-2345
Liu, F., Qin, Y., Yu, S., Soares, D.C., Yang, L., Weng, J., Li, C., Gao, M., Lu, Z., Hu, X., Liu, X., Jiang, T., Liu, J.Y., Shu, X., Tang, Z., Liu, M. (2017) Pathogenic Mutations in Retinitis Pigmentosa 2 Predominantly Result in Loss of RP2 Protein Stability in Human and Zebrafish. The Journal of biological chemistry. 292(15):6225-6239
Lu, Z., Hu, X., Liu, F., Soares, D.C., Liu, X., Yu, S., Gao, M., Han, S., Qin, Y., Li, C., Jiang, T., Luo, D., Guo, A.Y., Tang, Z., Liu, M. (2017) Ablation of EYS in zebrafish causes mislocalisation of outer segment proteins, F-actin disruption and cone-rod dystrophy. Scientific Reports. 7:46098
Raghupathy, R.K., Zhang, X., Alhasani, R.H., Zhou, X., Mullin, M., Reilly, J., Li, W., Liu, M., Shu, X. (2016) Abnormal photoreceptor outer segment development and early retinal degeneration in kif3a mutant zebrafish. Cell biochemistry and function. 34(6):429-40
Liu, F., Chen, J., Yu, S., Raghupathy, R.K., Liu, X., Qin, Y., Li, C., Huang, M., Liao, S., Wang, J., Zou, J., Shu, X., Tang, Z., Liu, M. (2015) Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish. Human molecular genetics. 24(16):4648-59
Dai, Z., Wang, H., Jin, X., Wang, H., He, J., Liu, M., Yin, Z., Sun, Y., Lou, Q. (2015) Depletion of suppressor of cytokine signaling-1a causes hepatic steatosis and insulin resistance in zebrafish. American journal of physiology. Endocrinology and metabolism. 308(10):E849-59
Li, C., Wang, L., Zhang, J., Huang, M., Wong, F., Liu, X., Liu, F., Cui, X., Yang, G., Chen, J., Liu, Y., Wang, J., Liao, S., Gao, M., Hu, X., Shu, X., Wang, Q., Yin, Z., Tang, Z., Liu, M. (2014) CERKL interacts with mitochondrial TRX2 and protects retinal cells from oxidative stress-induced apoptosis. Biochimica et biophysica acta. Molecular basis of disease. 1842(7):1121-9
Zhang, J., Cui, X., Wang, L., Liu, F., Jiang, T., Li, C., Li, D., Huang, M., Liao, S., Wang, J., Chen, J., Jia, H., He, J., Tang, Z., Yin, Z., Liu, M. (2014) The Mitochondrial Thioredoxin is Required for Liver Development in Zebrafish. Current Molecular Medicine. 14(6):772-82
Cui, X., Wang, L., Zhang, J., Du, R., Liao, S., Li, D., Li, C., Ke, T., Li, D.W., Huang, H., Yin, Z., Tang, Z., and Liu, M. (2013) HSF4 regulates DLAD expression and promotes lens de-nucleation. Biochimica et biophysica acta. Molecular basis of disease. 1832(8):1167-72
Cui, X., Zhang, J., Du, R., Wang, L., Archacki, S., Zhang, Y., Yuan, M., Ke, T., Li, H., Li, D., Li, C., Li, D.W., Tang, Z., Yin, Z., and Liu, M. (2012) HSF4 is involved in DNA damage repair through regulation of Rad51. Biochimica et biophysica acta. Molecular basis of disease. 1822(8):1308-1315

NON-ZEBRAFISH PUBLICATIONS