ZFIN Person: Sauka-Spengler, Tatjana

ZFIN ID: ZDB-PERS-140402-1

Sauka-Spengler, Tatjana

Email:	tatjana.sauka-spengler@imm.ox.ac.uk
URL:
Affiliation:	Sauka-Spengler Lab
Address:	MRC Weatherall Institute of Molecular Medicine Radcliffe Department of Medicine University of Oxford Headington, Oxford OX3 9DS
Country:
Phone:	+ 44 1865 222 810
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ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Weinberger, M., Simões, F.C., Gungoosingh, T., Sauka-Spengler, T., Riley, P.R. (2024) Distinct epicardial gene regulatory programs drive development and regeneration of the zebrafish heart. Developmental Cell. 59(3):351-367.e6

Chong-Morrison, V., Mayes, S., Simões, F.C., Senanayake, U., Carroll, D.S., Riley, P.R., Wilson, S.W., Sauka-Spengler, T. (2023) Ac/Ds transposition for CRISPR/dCas9-SID4x epigenome modulation in zebrafish. Biology Open. 12(6):

Lukoseviciute, M., Ling, I.T.C., Senanayake, U., Candido-Ferreira, I., Taylor, G., Williams, R.M., Sauka-Spengler, T. (2020) Tissue-Specific In Vivo Biotin Chromatin Immunoprecipitation with Sequencing in Zebrafish and Chicken. STAR protocols. 1:100066

Weinberger, M., Simões, F.C., Patient, R., Sauka-Spengler, T., Riley, P.R. (2020) Functional Heterogeneity within the Developing Zebrafish Epicardium. Developmental Cell. 52(5):574-590.e6

Simões, F.C., Cahill, T.J., Kenyon, A., Gavriouchkina, D., Vieira, J.M., Sun, X., Pezzolla, D., Ravaud, C., Masmanian, E., Weinberger, M., Mayes, S., Lemieux, M.E., Barnette, D.N., Gunadasa-Rohling, M., Williams, R.M., Greaves, D.R., Trinh, L.A., Fraser, S.E., Dallas, S.L., Choudhury, R.P., Sauka-Spengler, T., Riley, P.R. (2020) Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair. Nature communications. 11:600

Pinkwart, K., Schneider, F., Lukoseviciute, M., Sauka-Spengler, T., Lyman, E., Eggeling, C., Sezgin, E. (2019) Nanoscale dynamics of cholesterol in the cell membrane. The Journal of biological chemistry. 294:12599-12609

Lukoseviciute, M., Gavriouchkina, D., Williams, R.M., Hochgreb-Hagele, T., Senanayake, U., Chong-Morrison, V., Thongjuea, S., Repapi, E., Mead, A., Sauka-Spengler, T. (2018) From Pioneer to Repressor: Bimodal foxd3 Activity Dynamically Remodels Neural Crest Regulatory Landscape In Vivo. Developmental Cell. 47:608-628.e6

Trinh, L.A., Chong-Morrison, V., Sauka-Spengler, T. (2018) Biotagging, an in vivo biotinylation approach for cell-type specific subcellular profiling in zebrafish. Methods (San Diego, Calif.). 150:24-31

Kenyon, A., Gavriouchkina, D., Zorman, J., Chong-Morrison, V., Napolitani, G., Cerundolo, V., Sauka-Spengler, T. (2018) Generation of a double binary transgenic zebrafish model to study myeloid gene regulation in response to oncogene activation in melanocytes. Disease models & mechanisms. 11(4)

Kenyon, A., Gavriouchkina, D., Zorman, J., Napolitani, G., Cerundolo, V., Sauka-Spengler, T. (2017) Active nuclear transcriptome analysis reveals inflammasome-dependent mechanism for early neutrophil response to Mycobacterium marinum. Scientific Reports. 7:6505

Trinh, L.A., Chong-Morrison, V., Gavriouchkina, D., Hochgreb-Hägele, T., Senanayake, U., Fraser, S.E., Sauka-Spengler, T. (2017) Biotagging of Specific Cell Populations in Zebrafish Reveals Gene Regulatory Logic Encoded in the Nuclear Transcriptome. Cell Reports. 19:425-440

Falletta, P., Sanchez-Del-Campo, L., Chauhan, J., Effern, M., Kenyon, A., Kershaw, C.J., Siddaway, R., Lisle, R., Freter, R., Daniels, M.J., Lu, X., Tüting, T., Middleton, M., Buffa, F.M., Willis, A.E., Pavitt, G., Ronai, Z.A., Sauka-Spengler, T., Hölzel, M., Goding, C.R. (2017) Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma. Genes & Development. 31:18-33

Choi, H.M., Calvert, C.R., Husain, N., Huss, D., Barsi, J.C., Deverman, B.E., Hunter, R.C., Kato, M., Lee, S.M., Abelin, A.C., Rosenthal, A.Z., Akbari, O.S., Li, Y., Hay, B.A., Sternberg, P.W., Patterson, P.H., Davidson, E.H., Mazmanian, S.K., Prober, D.A., van de Rijn, M., Leadbetter, J.R., Newman, D.K., Readhead, C., Bronner, M.E., Wold, B., Lansford, R., Sauka-Spengler, T., Fraser, S.E., Pierce, N.A. (2016) Mapping a multiplexed zoo of mRNA expression. Development (Cambridge, England). 143:3632-3637

Bogdanović, O., Smits, A.H., de la Calle Mustienes, E., Tena, J.J., Ford, E., Williams, R., Senanayake, U., Schultz, M.D., Hontelez, S., van Kruijsbergen, I., Rayon, T., Gnerlich, F., Carell, T., Veenstra, G.J., Manzanares, M., Sauka-Spengler, T., Ecker, J.R., Vermeulen, M., Gómez-Skarmeta, J.L., Lister, R. (2016) Active DNA demethylation at enhancers during the vertebrate phylotypic period. Nature Genetics. 48(4):417-26

Gu, W., Monteiro, R., Zuo, J., Simões, F.C., Martella, A., Andrieu-Soler, C., Grosveld, F., Sauka-Spengler, T., Patient, R. (2015) A Novel TGFβ Modulator that Uncouples R-Smad/I-Smad-Mediated Negative Feedback from R-Smad/Ligand-Driven Positive Feedback. PLoS Biology. 13:e1002051

Bassett, A.R., Azzam, G., Wheatley, L., Tibbit, C., Rajakumar, T., McGowan, S., Stanger, N., Ewels, P.A., Taylor, S., Ponting, C.P., Liu, J.L., Sauka-Spengler, T., Fulga, T.A. (2014) Understanding functional miRNA-target interactions in vivo by site-specific genome engineering. Nature communications. 5:4640

NON-ZEBRAFISH PUBLICATIONS